Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.64 |
| ▸ | IDO1 | P14902 | 2/20 | 0.61 |
| ▸ | AGXT | P21549 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13788789 | 0.84 | IDO1 (0.62) | MAOBIDO1AGXTABCB1HTR1A | |
| SCHEMBL6567301 | 0.82 | IDO1 (0.89) | MAOBIDO1AGXTABCB1HTR1A | |
| SCHEMBL13263642 | 0.81 | MAOB (0.79) | MAOBIDO1AGXTBCHEABCB1 | |
| SCHEMBL9681686 | 0.81 | IDO1 (0.59) | MAOBIDO1AGXTCHRM2CHRM1 | |
| SCHEMBL31264 | 0.79 | IDO1 (0.71) | MAOBIDO1AGXTABCB1HTR1A | |
| SCHEMBL3768643 | 0.79 | IDO1 (0.71) | MAOBIDO1AGXTABCB1HTR1A | |
| SCHEMBL791569 | 0.78 | MAOB (1.00) | MAOBBCHEABCB1HTR1ADRD2 | |
| SCHEMBL15730033 | 0.77 | MAOB (0.62) | MAOBIDO1AGXTBCHEABCB1 | |
| SCHEMBL4060273 | 0.77 | TAAR1 (0.69) | MAOBIDO1AGXTABCB1HTR1A | |
| SCHEMBL2092574 | 0.77 | LTA4H (0.67) | MAOBIDO1AGXTCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404648-A1 | AMIDINE SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES WITH AN ANTITHROMBOTIC AND FACTOR XA INHIBITING ACTION | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003101942-A1 | AMIDINE SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES WITH AN ANTITHROMBOTIC AND FACTOR XA INHIBITING ACTION | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-12-11 | — | — | WO | disclosed |