SCHEMBL6567365

SCHEMBL6567365

CC(C)(C)CC(C)(C)c1cc(Cc2[c]c(C(C)(C)C)cc(C(C)(C)CC(C)(C)C)c2)[c]c(C(C)(C)C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.37
CYP3A4 P08684 4/20 0.31
HIF1A Q16665 2/20 0.31
IDH1 O75874 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
ESR1 P03372 1/20 0.31
TP53 P04637 1/20 0.31
PGR P06401 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
AR P10275 1/20 0.31
MAPT P10636 1/20 0.31
DRD1 P21728 1/20 0.31
PTGS1 P23219 1/20 0.31
SLC6A2 P23975 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5054603 0.91 SHBG (0.38) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL8961124 0.88 SHBG (0.42) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL1291247 0.84 GABRA1 (0.34)
SCHEMBL15067135 0.83 SHBG (0.38) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL6567366 0.78 CNR2 (0.43)
SCHEMBL11299088 0.78 SHBG (0.43) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL5053443 0.76 NPC1 (0.32) SMN1; SMN2MAPTMAPK1
SCHEMBL15067863 0.73 SHBG (0.39) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL2973654 0.73 HSPA5 (0.38)
SCHEMBL1720320 0.72 HTR1D (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1484334-A2 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-08 EP disclosed
US-20040225145-A1 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED 2004-11-11 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040225145-A1 Process for producing phosphite PHOSPHO1, PLCG1, PLCG2 SHBG 4506/4885CYP3A4 1993/4885HIF1A 2736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.