Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | DDX3X | O00571 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347676 | 0.87 | CXCR1 (0.68) | CXCR2KMT2AMEN1DDX3XCA12 | |
| SCHEMBL6566895 | 0.86 | CXCR2 (0.66) | CXCR2KMT2AMEN1DDX3XPOLB | |
| SCHEMBL5595289 | 0.84 | CXCR1 (0.73) | CXCR2KMT2AMEN1POLBHTT | |
| SCHEMBL5605320 | 0.84 | CXCR2 (1.00) | CXCR2KMT2AMEN1DDX3XHTT | |
| SCHEMBL1275926 | 0.82 | RAB9A (0.75) | KMT2AMEN1DDX3XPOLBHTT | |
| SCHEMBL6568502 | 0.82 | RAB9A (0.68) | CXCR2KMT2AMEN1CA12CA1 | |
| SCHEMBL27576146 | 0.82 | CXCR2 (0.69) | CXCR2KMT2AMEN1CA12CA1 | |
| SCHEMBL3710548 | 0.81 | CXCR2 (0.71) | CXCR2DDX3XCA12CA1CA2 | |
| SCHEMBL5852144 | 0.80 | LPAR1 (0.71) | KMT2AMEN1DDX3XPOLBALDH1A1 | |
| SCHEMBL5594962 | 0.80 | MEN1 (0.72) | CXCR2KMT2AMEN1DDX3XCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |