SCHEMBL1275926

SCHEMBL1275926

Cc1ccccc1NC(=O)Nc1ccccc1C

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.75
NPC1 O15118 3/20 0.75
DDX3X O00571 2/20 0.75
ALDH1A1 P00352 2/20 0.72
HPGD P15428 2/20 0.72
POLB P06746 3/20 0.71
MAPT P10636 4/20 0.68
L3MBTL1 Q9Y468 2/20 0.68
TP53 P04637 1/20 0.68
GAA P10253 1/20 0.68
ALOX15 P16050 1/20 0.68
HSD17B10 Q99714 1/20 0.68
ITGB3 P05106 2/20 0.67
ITGAV P06756 2/20 0.67
ITGB1 P05556 1/20 0.67
ITGA5 P08648 1/20 0.67
HTT P42858 2/20 0.64
MEN1 O00255 1/20 0.64
KMT2A Q03164 1/20 0.64
NPSR1 Q6W5P4 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL812756 0.90 DDX3X (0.80) RAB9ANPC1DDX3XALDH1A1HPGD
SCHEMBL8369698 0.89 ALDH1A1 (0.76) RAB9ANPC1DDX3XALDH1A1HPGD
SCHEMBL28250804 0.88 POLB (0.64) RAB9ANPC1DDX3XALDH1A1HPGD
SCHEMBL5475011 0.87 POLB (0.68) RAB9ANPC1DDX3XALDH1A1HPGD
SCHEMBL8334833 0.87 RAB9A (0.64) RAB9ANPC1DDX3XALDH1A1HPGD
SCHEMBL8421705 0.87 RAB9A (0.64) RAB9ANPC1DDX3XALDH1A1HPGD
SCHEMBL1659299 0.87 DDX3X (1.00) RAB9ANPC1DDX3XALDH1A1HPGD
SCHEMBL11918074 0.87 DDX3X (1.00) RAB9ANPC1DDX3XALDH1A1HPGD
SCHEMBL5852186 0.87 DDX3X (0.70) RAB9ANPC1DDX3XALDH1A1HPGD
SCHEMBL5605545 0.87 KDM4E (0.64) RAB9ANPC1DDX3XALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7666977-B2 Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-02-23 US claimed
US-20080306237-A1 Highly Functional, Highly Branched Polyureas BASF AKTIENGESELLSCHAFT (DE) 2008-12-11 US claimed
WO-2008136841-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-11-13 WO claimed
US-20080275209-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2008-11-06 US claimed
EP-1716197-B1 HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS BASF SE (DE) 2008-10-29 EP claimed
CN-118684599-A Preparation method of N, N-diaryl urea compound 上海应用技术大学 2024-09-24 CN disclosed
CN-117024713-A Preparation method of synthetic silane coupling agent catalyst 苏州市贝特利高分子材料股份有限公司 2023-11-10 CN disclosed
CN-114605408-B 5-hydroxy-1, 3-disubstituted phenylpyrido [2,3-d ] pyrimidine compound and preparation method and application thereof 沈阳药科大学 2023-06-16 CN disclosed
CN-112920089-B Method for synthesizing substituted urea compound by photocatalysis 湖南中医药大学 2023-05-12 CN disclosed
CN-114213286-B Synthetic method of urea derivative 湖北文理学院 2022-12-30 CN disclosed
CN-112679364-B Synthetic method of dasatinib key raw material 2-chloro-6-methylaniline 山东铂源药业股份有限公司 2022-11-18 CN disclosed
CN-111770972-B Silver nanowire ink and transparent conductive film 昭和电工株式会社 2022-07-01 CN disclosed
US-20080275206-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2008-11-06 US disclosed
US-20080275209-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2008-11-06 US disclosed
US-5194660-A Processes for producing carbamates and isocyanates UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-03-16 US disclosed
EP-0083096-B1 PRODUCTION OF URETHANE COMPOUNDS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-02-25 EP disclosed
US-4621149-A PLATINUM GROUP METAL HALOGEN OR HALOGEN COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1986-11-04 US disclosed
EP-0083096-A2 Production of urethane compounds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-07-06 EP disclosed
US-4304922-A REDOX SYSTEMS COMPRISING A UREA, AN ALCOHOL, CARBON MONOXIDE, OXYGEN, A REDUCIBLE METAL SALT, AND A CATALYTIC GROUP 8 METAL SALT BAYER AKTIENGESELLSCHAFT (DE) 1981-12-08 US disclosed
US-4080365-A Process for preparing aromatic urethanes MITSUI TOATSU CHEMICALS (JA) 1978-03-21 US disclosed