Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.40 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.40 |
| ▸ | DUT | P33316 | 3/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14143399 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KMT2ALMNAPOLBESR1 | |
| SCHEMBL7672062 | 0.77 | SLC28A1 (0.40) | LMNAESR1MAPTSLC28A1SLC28A2 | |
| SCHEMBL2922882 | 0.76 | SLC28A1 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL12062407 | 0.74 | HCAR1 (0.49) | SLC28A1SLC28A2SLC29A1SLC28A3CRBN | |
| SCHEMBL8087495 | 0.74 | SLC28A1 (0.47) | ALDH1A1KMT2ASMN1; SMN2MEN1SLC28A1 | |
| SCHEMBL26916149 | 0.73 | CRBN (0.47) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL20281116 | 0.73 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL9853759 | 0.73 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL13531639 | 0.73 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL18744090 | 0.73 | SLC28A1 (0.41) | ALDH1A1KMT2ALMNAPOLBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401425-A1 | ORGANOMETALLIC ANTI-TUMOUR AGENT | Haemato-Basics GmbH (DE) | 2004-03-31 | — | — | EP | claimed |
| WO-2003004014-A1 | ORGANOMETALLIC ANTI-TUMOUR AGENT | HAEMATO-BASICS GMBH (DE) | 2003-01-16 | — | — | WO | claimed |
| JP-54052085-A | — | — | None | — | — | JP | disclosed |
| JP-53021178-A | — | — | None | — | — | JP | disclosed |
| EP-4452934-A1 | IONIZABLE DISULFIDE LIPIDS AND LIPID NANOPARTICLES DERIVED THEREFROM | Providence Therapeutics Holdings Inc. (CA) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023115221-A1 | IONIZABLE DILSULFIDE LIPIDS AND LIPID NANOPARTICLES DERIVED THEREFROM | PROVIDENCE THERAPEUTICS HOLDINGS INC. (CA) | 2023-06-29 | — | — | WO | disclosed |
| CN-113166190-B | Oligonucleotides and prodrugs | 正大天晴药业集团股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2018107236-A1 | NOVEL COMPOUNDS AS ANTI-MYCOBACTERIALS | THE UNIVERSITY OF SYDNEY (AU) | 2018-06-21 | — | — | WO | disclosed |
| EP-0877022-B1 | Sulfonylpyrimidine derivatives with anticancer activity | RUDJER BOSKOVIC INST (HR) | 2003-04-16 | — | — | EP | disclosed |
| US-5075446-A | Synthesis of tetrahydro-2-furylated pyrimidine derivatives | KOREA ADVANCED INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 1991-12-24 | — | — | US | disclosed |
| US-4650801-A | CYTOSINE TO INHIBIT DECOMPOSITION | TAIHO PHARMACEUTICAL COMPANY, LTD. (JP) | 1987-03-17 | — | — | US | disclosed |
| EP-0079054-A1 | Enhancer of antitumor effect | Yamasa Shoyu Kabushiki Kaisha (JP) | 1983-05-18 | — | — | EP | disclosed |
| EP-0068268-A1 | Enhancer of anti-tumour effect | Yamasa Shoyu Kabushiki Kaisha (JP) | 1983-01-05 | — | — | EP | disclosed |
| EP-0048022-A2 | Enhancer of anti-tumor effect | Yamasa Shoyu Kabushiki Kaisha (JP) | 1982-03-24 | — | — | EP | disclosed |
| EP-0045944-A1 | Enhancer of anti-tumor effect | Yamasa Shoyu Kabushiki Kaisha (JP) | 1982-02-17 | — | — | EP | disclosed |
| JP-S5452085-A | PREPARATION OF URACIL DERIVATIVES | BANYU PHARMACEUT CO LTD | 1979-04-24 | — | — | JP | disclosed |
| JP-S5321178-A | PREPARATION OF 1-(2-TETRAHYDROFURYL)URACILS | KOHJIN CO LTD | 1978-02-27 | — | — | JP | disclosed |
| US-3960864-A | Method of synthesizing 1-(tetrahydro-2-furanyl)-5-fluorouracil | THE UNIVERSITY OF UTAH (US) | 1976-06-01 | — | — | US | disclosed |
| US-3948897-A | Synthesis of 1-(tetrahydro-2-furanyl)-5-fluorouracil (Ftorafur) via direct fluorination | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF HEALTH, EDUCATION AND WELFARE (US) | 1976-04-06 | — | — | US | disclosed |
| US-3948897-A | Synthesis of 1-(tetrahydro-2-furanyl)-5-fluorouracil (Ftorafur) via direct fluorination | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF HEALTH, EDUCATION AND WELFARE (US) | 1976-04-06 | — | — | US | disclosed |