Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895423 | 0.82 | PIN1 (0.41) | PIN1MEN1NPC1KMT2AMMP8 | |
| SCHEMBL9771779 | 0.77 | KMT2A (0.35) | MEN1KMT2APOLBPPARAPPARG | |
| SCHEMBL27546630 | 0.76 | MMP8 (0.56) | PIN1MMP8PPARAPPARGPPARD | |
| SCHEMBL3541115 | 0.76 | MMP8 (0.56) | PIN1MMP8PPARAPPARGPPARD | |
| SCHEMBL10434783 | 0.74 | PKM (0.45) | MEN1KMT2ATSHR | |
| SCHEMBL6718321 | 0.73 | CA12 (0.45) | PIN1MEN1NPC1KMT2AMMP8 | |
| SCHEMBL5872069 | 0.72 | PTPRB (0.43) | MEN1KMT2AMMP8POLBPPARA | |
| SCHEMBL1452075 | 0.72 | KDM4E (0.32) | — | |
| SCHEMBL11285611 | 0.71 | CYP4F2 (0.54) | TSHRTDP1CYP1A2CYP2C9 | |
| SCHEMBL2554435 | 0.70 | PPARA (0.52) | MEN1KMT2AMMP8PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404649-A1 | NEW PHENYLALKYLOXY-PHENYL DERIVATIVES | AstraZeneca AB (SE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002096863-A1 | NEW PHENYLALKYLOXY-PHENYL DERIVATIVES | ASTRAZENECA AB (SE) | 2002-12-05 | — | — | WO | disclosed |