SCHEMBL6567769

SCHEMBL6567769

CC1(C)OC[C@H]2O[C@@H](OCc3ccccc3)[C@H](N)[C@@H](O)[C@@H]2O1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ TACR1 P25103 1/20 0.35
▸ TMEM97 Q5BJF2 2/20 0.34
▸ SIGMAR1 Q99720 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ SLC6A2 P23975 1/20 0.34
▸ GJB2 P29033 2/20 0.34
▸ HRAS P01112 1/20 0.34
▸ YWHAZ P63104 2/20 0.33
▸ SSTR5 P35346 1/20 0.33
▸ GSTP1 P09211 2/20 0.32
▸ SLC5A2 P31639 1/20 0.32
▸ IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10831460 1.00 L3MBTL1 (0.39) L3MBTL1TACR1TMEM97SIGMAR1MEN1
SCHEMBL7154934 0.90 MEN1 (0.41) L3MBTL1TMEM97SIGMAR1MEN1KMT2A
SCHEMBL15890505 0.82 L3MBTL1 (0.40) L3MBTL1TMEM97SIGMAR1HRASGSTP1
SCHEMBL5308210 0.82 L3MBTL1 (0.54) L3MBTL1TMEM97SIGMAR1KMT2AHRAS
SCHEMBL1836110 0.82 L3MBTL1 (0.54) L3MBTL1TMEM97SIGMAR1KMT2AHRAS
SCHEMBL16153926 0.82 SLC6A2 (0.47) SLC6A2GJB2HRAS
SCHEMBL10832391 0.81 L3MBTL1 (0.41) L3MBTL1TACR1TMEM97SIGMAR1MEN1
SCHEMBL13953444 0.81 MEN1 (0.39) L3MBTL1TACR1TMEM97SIGMAR1MEN1
SCHEMBL8720842 0.81 MEN1 (0.39) L3MBTL1TACR1TMEM97SIGMAR1MEN1
SCHEMBL15012280 0.80 L3MBTL1 (0.46) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0224260-A2 Analogs of nonreducing monosaccharide moiety of lipid A Toho Yakuhin Kogyo Kabushiki Kaisha (JP) 1987-06-03 — — EP claimed
JP-62129292-A — — None — — JP disclosed
JP-1213290-A — — None — — JP disclosed
JP-63044588-A — — None — — JP disclosed
EP-1105401-B1 PHOSPHOGLYCOLIPID AND METHODS FOR ITS USE CORIXA CORP (US) 2004-04-07 — — EP disclosed
US-20020013291-A1 Phosphoglycolipid and methods for its use CORIXA CORPORATION 2002-01-31 — — US disclosed
EP-1105401-A1 PHOSPHOGLYCOLIPID AND METHODS FOR ITS USE CORIXA CORPORATION (US) 2001-06-13 — — EP disclosed
WO-2000011010-A1 PHOSPHOGLYCOLIPID AND METHODS FOR ITS USE CORIXA CORPORATION (US) 2000-03-02 — — WO disclosed
US-6013640-A ANTIISCHEMIC AGENTS RIBI IMMUNOCHEM RESEARCH, INC. (US) 2000-01-11 — — US disclosed
US-RE36385-E TREATMENT OF TUMORS, ENHANCING IMMUNITY ONO PHARMACEUTICAL CO., LTD. (JP) 1999-11-09 — — US disclosed
EP-0288888-B1 Novel glucopyranose derivatives ONO PHARMACEUTICAL CO (JP) 1993-12-08 — — EP disclosed
US-4925929-A ANTITUMOR AGENTS ONO PHARMACEUTICAL CO. LTD. (JP) 1990-05-15 — — US disclosed
JP-H01213290-A NOVEL PHOSPHORYL GLUCOSAMINE DERIVATIVE TOHO YAKUHIN KOGYO KK 1989-08-28 — — JP disclosed
EP-0288888-A2 Novel glucopyranose derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1988-11-02 — — EP disclosed
US-4746742-A IMMUNOLOGY, ANTI-TUMOR TOHO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1988-05-24 — — US disclosed
JP-S6344588-A LACTASE-TYPE ISOMER OF LIPID A MONOSACCHARIDE ANALOG TOHO YAKUHIN KOGYO KK 1988-02-25 — — JP disclosed
JP-S62129292-A LIPID A MONOSACCHARIDE RELATED SUBSTANCE DEVELOPING BIOLOGICAL ACTIVITY TOHO YAKUHIN KOGYO KK 1987-06-11 — — JP disclosed
EP-0224260-A2 Analogs of nonreducing monosaccharide moiety of lipid A Toho Yakuhin Kogyo Kabushiki Kaisha (JP) 1987-06-03 — — EP disclosed
EP-0188697-A2 2-deoxy-4-0-phosphoryl-2-[(3'-0-tetradecanoyl)-tetradecanoylamino]-3-0-tetradecanoyl-D-glucose and stereoisomers thereof Toho Yakuhin Kogyo Kabushiki Kaisha (JP) 1986-07-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013291-A1 Phosphoglycolipid and methods for its use PYGL, GPI, PNLIP L3MBTL1 635/4885TACR1 2840/4885TMEM97 2675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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