Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 12/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22895128 | 0.85 | TGM2 (0.60) | TGM2 | |
| SCHEMBL14317559 | 0.81 | ATM (0.54) | ATMCTSSCTSLCTSKCTSB | |
| SCHEMBL16473698 | 0.81 | ATM (0.54) | ATMCTSSCTSLCTSKCTSB | |
| SCHEMBL14247228 | 0.81 | ATM (0.54) | ATMCTSSCTSLCTSKCTSB | |
| SCHEMBL30356478 | 0.81 | LMNA (0.52) | ATMCTSSCTSLCTSKSYK | |
| SCHEMBL4251984 | 0.81 | ATM (0.57) | ATMCTSSCTSLCTSKSYK | |
| SCHEMBL4251981 | 0.81 | ATM (0.57) | ATMCTSSCTSLCTSKSYK | |
| SCHEMBL2627371 | 0.80 | SYK (0.74) | ATMCTSSCTSLCTSKSYK | |
| SCHEMBL6312567 | 0.80 | SYK (0.74) | ATMCTSSCTSLCTSKSYK | |
| SCHEMBL6312582 | 0.80 | SYK (0.74) | ATMCTSSCTSLCTSKSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147076-B1 | ACRYLAMIDE DERIVATIVES AND POLYMERS CONTAINING SAID DERIVATIVES | OKANO TERUO PROF (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6495645-B1 | INCORPORATING MANY SIDE FUNCTIONAL GROUPS WHILE MAINTAINING SENSITIVE TEMPERATURE RESPONSE | Okano, Terou (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-1147076-A1 | ACRYLAMIDE DERIVATIVES AND POLYMERS CONTAINING SAID DERIVATIVES | Amersham Pharmacia Biotech K.K. (JP) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000043355-A1 | ACRYLAMIDE DERIVATIVES AND POLYMERS CONTAINING SAID DERIVATIVES | AMERSHAM PHARMACIA BIOTECH K.K. (JP) | 2000-07-27 | — | — | WO | disclosed |