Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11688563 | 0.97 | CES2 (0.50) | THRATHRBCES2CES1HDAC8 | |
| SCHEMBL18849431 | 0.97 | CES2 (0.50) | THRATHRBCES2CES1HDAC8 | |
| SCHEMBL761937 | 0.97 | CES2 (0.50) | THRATHRBCES2CES1HDAC8 | |
| SCHEMBL1581889 | 0.95 | — | — | |
| SCHEMBL1056492 | 0.90 | — | — | |
| SCHEMBL24851670 | 0.89 | THRA (0.44) | THRATHRBCES2CES1HDAC8 | |
| SCHEMBL24852405 | 0.87 | THRA (0.43) | THRATHRBCES2CES1HDAC8 | |
| SCHEMBL22457958 | 0.87 | THRA (0.43) | THRATHRBCES2CES1HDAC8 | |
| SCHEMBL20800026 | 0.87 | THRA (0.47) | THRATHRBCES2CES1HDAC8 | |
| SCHEMBL24852366 | 0.87 | THRA (0.47) | THRATHRBCES2CES1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478403-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA, INC. (CA) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003063909-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA INC. (US) | 2003-08-07 | — | — | WO | disclosed |