SCHEMBL761937

SCHEMBL761937

C=CC(=O)C1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
THRA P10827 1/20 0.50
THRB P10828 1/20 0.50
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
TSHR P16473 3/20 0.41
ALDH1A1 P00352 1/20 0.41
HSD11B1 P28845 3/20 0.37
EPHX1 P07099 4/20 0.35
RECQL P46063 1/20 0.35
SRD5A2 P31213 1/20 0.35
HSD11B2 P80365 1/20 0.34
MAPK1 P28482 1/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11688563 1.00 CES2 (0.50) CES2CES1THRATHRBHDAC8
SCHEMBL18849431 1.00 CES2 (0.50) CES2CES1THRATHRBHDAC8
Ammonia Solution, Strong SCHEMBL6567907 0.97 THRA (0.48) CES2CES1THRATHRBHDAC8
SCHEMBL1581889 0.97
SCHEMBL1056492 0.92
SCHEMBL24851670 0.91 THRA (0.44) CES2CES1THRATHRBHDAC8
SCHEMBL24852366 0.89 THRA (0.47) CES2CES1THRATHRBHDAC8
SCHEMBL22457958 0.89 THRA (0.43) CES2CES1THRATHRBHDAC8
SCHEMBL20800026 0.89 THRA (0.47) CES2CES1THRATHRBHDAC8
SCHEMBL24852405 0.89 THRA (0.43) CES2CES1THRATHRBHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115650837-B Method for preparing ketone compound by 1,4 addition reaction of alpha, beta unsaturated ketene 南京工业大学 2024-05-17 CN claimed
CN-115650837-A Method for preparing ketone compound by utilizing 1,4 addition reaction of alpha, beta unsaturated ketene 南京工业大学 2023-01-31 CN claimed
WO-1991018861-A1 2-(HYDROXYMETHYL) ACRYLATE DERIVATIVES AND PROCESS FOR THEIR PREPARATION COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1991-12-12 WO claimed
US-3997708-A ADDITION PHILLIPS PETROLEUM COMPANY (US) 1976-12-14 US claimed
JP-6192142-A None JP disclosed
EP-4692042-A1 COMPOUND, POLYMERIZABLE COMPOSITION, HOLOGRAM RECORDING MEDIUM, POLYMER, OPTICAL MATERIAL, AND OPTICAL COMPONENT Mitsubishi Chemical Corporation (JP) 2026-02-11 EP disclosed
US-20260034094-A1 COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS KOJIN THERAPEUTICS INC (US) 2026-02-05 US disclosed
US-20260028312-A1 COMPOUND, POLYMERIZABLE COMPOSITION, HOLOGRAM RECORDING MEDIUM, POLYMER, OPTICAL MATERIAL, AND OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2026-01-29 US disclosed
EP-4632110-A1 PROCESS FOR THE HALOGENATION OF ORGANIC COMPOUNDS ESy-Labs-GmbH (DE) 2025-10-15 EP disclosed
EP-4606785-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAM RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT Mitsubishi Chemical Corporation (JP) 2025-08-27 EP disclosed
US-20250206731-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2025-06-26 US disclosed
EP-4565228-A2 COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS Kojin Therapeutics, Inc. (US) 2025-06-11 EP disclosed
EP-0002258-A2 Hydantoin derivatives and salts thereof, their synthesis and intermediates, and pharmaceutical formulations THE WELLCOME FOUNDATION LIMITED (GB) 1979-06-13 EP disclosed
EP-0001238-A1 Hydantoin derivatives, their synthesis, pharmaceutical formulations and intermediates in their preparation THE WELLCOME FOUNDATION LIMITED (GB) 1979-04-04 EP disclosed
US-4121032-A Process for preparing alternating copolymer of conjugated vinyl compound and olefinic unsaturated compound with oxygen and boron compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-10-17 US disclosed
US-4061638-A Organocalciumpyridine-type polymerization initiators PHILLIPS PETROLEUM COMPANY (US) 1977-12-06 US disclosed
US-4046577-A PHOTOREACTIVE COMPOSITIONS COMPRISING POLYMERS CONTAINING ALKOXYAROMATIC GLYOXY GROUPS THE RICHARDSON COMPANY (US) 1977-09-06 US disclosed
US-3989882-A Process for preparing an alternating copolymer of a conjugated vinyl compound and an olefinic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-11-02 US disclosed
US-3984599-A MINERAL OIL, WAXES, WAX CRYSTAL MODIFIER EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-10-05 US disclosed
US-3936473-A COPPER OR NOBLE METAL SALT, OXYGEN AND ORGANIC ACID CATALYST UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028312-A1 COMPOUND, POLYMERIZABLE COMPOSITION, HOLOGRAM RECORDING MEDIUM, POLYMER, OPTICAL MATERIAL, AND OPTICAL COMPONENT CHRM1, CHRM2, NOX1 CES2 3781/4885CES1 2933/4885THRA 2020/4885
US-20250206731-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT H1-0, H1-3, H1-2 CES2 4664/4885CES1 4602/4885THRA 4425/4885
US-20260034094-A1 COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS AIFM2, GPX4, HMOX1 CES2 3131/4885CES1 2029/4885THRA 1716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.