SCHEMBL65682

SCHEMBL65682

O=C(O)c1ccc(N2CCCCC2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.67
NPC1 O15118 5/20 0.67
RAB9A P51151 5/20 0.67
HPGD P15428 4/20 0.67
MAPT P10636 4/20 0.67
TP53 P04637 4/20 0.67
SMN1; SMN2 Q16637 4/20 0.67
HSD17B10 Q99714 3/20 0.67
L3MBTL1 Q9Y468 3/20 0.67
ALOX15 P16050 3/20 0.67
TSHR P16473 2/20 0.67
LMNA P02545 1/20 0.67
STAT1 P42224 1/20 0.67
KDM4E B2RXH2 6/20 0.65
USP2 O75604 1/20 0.62
HDAC6 Q9UBN7 1/20 0.61
GAA P10253 3/20 0.59
MAPK1 P28482 2/20 0.59
CASP1 P29466 1/20 0.59
CASP7 P55210 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17737071 1.00 ALDH1A1 (0.67) ALDH1A1NPC1RAB9AHPGDMAPT
SCHEMBL13850382 1.00 ALDH1A1 (0.67) ALDH1A1NPC1RAB9AHPGDMAPT
SCHEMBL419882 0.98 ALDH1A1 (0.69) ALDH1A1NPC1RAB9AHPGDMAPT
SCHEMBL22442320 0.94 KDM4E (0.67) ALDH1A1NPC1RAB9AHPGDMAPT
SCHEMBL20193318 0.92 KDM4E (0.65) ALDH1A1NPC1RAB9AHPGDMAPT
SCHEMBL18821871 0.89 NPC1 (0.64) ALDH1A1NPC1RAB9AHPGDMAPT
SCHEMBL23610369 0.89 KDM4E (0.71) ALDH1A1NPC1RAB9AHPGDMAPT
SCHEMBL17737082 0.89 KDM4E (0.71) ALDH1A1NPC1RAB9AHPGDMAPT
SCHEMBL18821570 0.87 MAPT (0.63) ALDH1A1NPC1RAB9AHPGDMAPT
SCHEMBL2975193 0.85 NPC1 (0.82) ALDH1A1NPC1RAB9AHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116497411-A Cyanide-free alkaline silver plating electroplating solution and preparation and application thereof 上海电力大学 2023-07-28 CN claimed
EP-2350311-B1 DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS MADRIGAL PHARMACEUTICALS INC (US) 2013-12-25 EP claimed
EP-2350311-A1 DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS Via Pharmaceuticals, Inc. (US) 2011-08-03 EP claimed
WO-2010056506-A1 DIACYLGLYCEROL ACLYTRANSFERASE INHIBITORS VIA PHARMACEUTICALS, INC. (US) 2010-05-20 WO claimed
US-20100113782-A1 Diacylglycerol Acyltransferase Inhibitors MADRIGAL PHARMACEUTICALS, INC. 2010-05-06 US claimed
EP-0623635-B1 Amine-functionalized polyester GEN ELECTRIC (US) 2003-02-19 EP claimed
EP-0157472-B1 PROCESS FOR POLYMERIZATION OF OLEFINS TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1990-03-07 EP claimed
JP-57095976-A None JP disclosed
CN-120192315-A Echinococcosis-resistant medicine and preparation method and application thereof 新疆医科大学 2025-06-24 CN disclosed
US-12187911-B2 Method for preparing water-soluble acrylic-modified phenolic-modified epoxy resin, water-soluble acrylic-modified phenolic-modified epoxy resin prepared thereby, and aqueous coating composition comprising same SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) 2025-01-07 US disclosed
CN-118652243-A Peroxisome proliferator-activated receptor (PPARs) agonist, preparation method and application thereof 中国医学科学院医药生物技术研究所 2024-09-17 CN disclosed
US-20240117213-A1 METHOD FOR PREPARING WATER-SOLUBLE ACRYLIC-MODIFIED PHENOLIC-MODIFIED EPOXY RESIN, WATER-SOLUBLE ACRYLIC-MODIFIED PHENOLIC-MODIFIED EPOXY RESIN PREPARED THEREBY, AND AQUEOUS COATING COMPOSITION COMPRISING SAME SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) 2024-04-11 US disclosed
CN-117136187-A Novel anti-hepatitis B compound 上海齐鲁制药研究中心有限公司 2023-11-28 CN disclosed
EP-0157472-B1 PROCESS FOR POLYMERIZATION OF OLEFINS TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1990-03-07 EP disclosed
EP-0155847-B1 A STABILIZER FOR SYNTHETIC RESINS AND RESINS STABILIZED THEREBY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-08 EP disclosed
EP-0171139-B1 HIGH POLYMER STABILIZER CONTAINING A PHENOLIC COMPOUND, AND HIGH POLYMERS STABILIZED THEREBY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-07-26 EP disclosed
EP-0156512-B1 PROCESS FOR PREPARING CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1989-06-14 EP disclosed
EP-0106618-B1 STABILIZERS FOR SYNTHETIC RESINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-02-10 EP disclosed
EP-0102193-B1 STABILIZERS FOR SYNTHETIC RESINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-10-29 EP disclosed
JP-S5795976-A PIPERIDINOPHENYLCARBOXYLIC ACID DERIVATIVE AND ITS PREPARATION NISSAN CHEM IND LTD 1982-06-15 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113782-A1 Diacylglycerol Acyltransferase Inhibitors DGAT2, DGAT1, MOGAT2 ALDH1A1 802/4885NPC1 432/4885RAB9A 2586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.