Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747916 | 0.94 | NR4A2 (0.47) | TSHRNR4A2ALDH1A1KMT2AMAPT | |
| SCHEMBL6570116 | 0.88 | TSHR (0.55) | TSHRNOTUMALDH1A1KMT2AMAPT | |
| SCHEMBL6571494 | 0.85 | ALDH1A1 (0.48) | NR4A2ALDH1A1KMT2AMAPTCYP1A2 | |
| SCHEMBL2158508 | 0.83 | ALDH1A1 (0.50) | TSHRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL16719289 | 0.78 | ALDH1A1 (0.42) | TSHRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL10103507 | 0.77 | HTR7 (0.47) | TSHRNR4A2ALDH1A1KMT2AMAPT | |
| SCHEMBL16719847 | 0.76 | KMT2A (0.47) | TSHRALDH1A1KMT2AMAPTCYP1A2 | |
| SCHEMBL22045254 | 0.76 | TP53 (0.53) | TSHRNR4A2ALDH1A1MAPTCYP2C19 | |
| SCHEMBL27862033 | 0.74 | ALDH1A1 (0.49) | TSHRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL2159577 | 0.74 | TSHR (0.54) | TSHRALDH1A1KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404644-A2 | NOVEL HYDRAZONES | Arpida AG, (CH) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002070464-A2 | HYDRAZONES AND THEIR THERAPEUTIC USE | ARPIDA AG (CH) | 2002-09-12 | — | — | WO | disclosed |