Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | AOC2 | O75106 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747916 | 0.90 | NR4A2 (0.47) | ALDH1A1NR4A2HPGDLMNAKMT2A | |
| SCHEMBL6569031 | 0.90 | ALDH1A1 (0.57) | ALDH1A1CTSDGAALMNAAOC2 | |
| SCHEMBL6568367 | 0.85 | TSHR (0.44) | ALDH1A1NR4A2HPGDLMNAKMT2A | |
| SCHEMBL2158508 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LMNAKMT2AMAPTCFTR | |
| SCHEMBL16719289 | 0.75 | ALDH1A1 (0.42) | ALDH1A1LMNAKMT2AMAPTCFTR | |
| SCHEMBL10103507 | 0.74 | HTR7 (0.47) | ALDH1A1NR4A2HPGDLMNAKMT2A | |
| SCHEMBL10074345 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HPGDLMNAKMT2AMAPT | |
| SCHEMBL16719847 | 0.73 | KMT2A (0.47) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL6570116 | 0.72 | TSHR (0.55) | ALDH1A1HPGDLMNAKMT2AMAPT | |
| SCHEMBL4015273 | 0.71 | CTSD (0.65) | ALDH1A1CTSDGAALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404644-A2 | NOVEL HYDRAZONES | Arpida AG, (CH) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002070464-A2 | HYDRAZONES AND THEIR THERAPEUTIC USE | ARPIDA AG (CH) | 2002-09-12 | — | — | WO | disclosed |