Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6566610 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL8153120 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL8161318 | 0.72 | ALOX15 (0.33) | NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL8160463 | 0.68 | — | — | |
| SCHEMBL9090818 | 0.68 | IGF1R (0.42) | NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL18663166 | 0.67 | IGF1R (0.32) | — | |
| Hydrochloric Acid SCHEMBL18663180 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL18663123 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL18663173 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL18663182 | 0.65 | IGF1R (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962474-B1 | Propylene block copolymer and resin composition | JAPAN POLYCHEM CORP (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6469100-B2 | COORDINATION CATALYST | JAPAN POLYCHEM CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| US-20010014719-A1 | PROPYLENE BLOCK COPOLYMER AND RESIN COMPOSITION | JAPAN POLYCHEM CORPORATION (JP) | 2001-08-16 | — | — | US | disclosed |
| EP-0962474-A1 | Propylene block copolymer and resin composition | Japan Polychem Corporation (JP) | 1999-12-08 | — | — | EP | disclosed |