Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920038 | 0.83 | AKR1C3 (0.40) | ALDH1A1HPGDHSD17B10AKR1C3MAPT | |
| SCHEMBL6816989 | 0.82 | HPGD (0.39) | ALDH1A1HPGDHSD17B10AKR1C3MAPT | |
| SCHEMBL6820885 | 0.80 | RAB9A (0.46) | ALDH1A1AKR1C3MAPTNPC1RAB9A | |
| SCHEMBL6817325 | 0.72 | MAPT (0.32) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6816878 | 0.67 | GPR35 (0.33) | ALDH1A1MAPT | |
| SCHEMBL7641650 | 0.66 | ITGAL (0.43) | ALDH1A1AKR1C3SMN1; SMN2KDM4E | |
| SCHEMBL6816992 | 0.65 | SLC6A4 (0.32) | — | |
| SCHEMBL23699463 | 0.64 | TSHR (0.48) | ALDH1A1HSD17B10MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6921375 | 0.63 | HPGD (0.34) | ALDH1A1HPGDHSD17B10AKR1C3NPC1 | |
| SCHEMBL11314457 | 0.60 | HPGD (0.40) | ALDH1A1HPGDHSD17B10AKR1C3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481968-A2 | Cell adhesion-inhibiting anti-inflammatory and immune-suppressive compounds | Abbott Laboratories (US) | 2004-12-01 | — | — | EP | disclosed |