Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377848 | 0.86 | ESR1 (0.56) | KDM4ETSHRCYP1A2CYP2C9HIF1A | |
| SCHEMBL3271558 | 0.84 | APP (0.53) | LMNAKDM4EPOLBTSHRCYP1A2 | |
| SCHEMBL28827968 | 0.83 | HPGD (0.62) | HTTLMNAKDM4EPOLBHPGD | |
| SCHEMBL2823002 | 0.83 | PPARD (0.52) | KDM4EPOLBTSHR | |
| SCHEMBL7015372 | 0.83 | AR (0.44) | HTTLMNAPOLBTSHRCYP1A2 | |
| SCHEMBL1549647 | 0.83 | VDR (0.46) | LMNAKDM4EPOLBTSHRCYP1A2 | |
| SCHEMBL3273629 | 0.83 | LMNA (0.64) | HTTLMNAKDM4ETSHRHPGD | |
| SCHEMBL3271015 | 0.83 | LMNA (0.47) | HTTLMNAKDM4EPOLBCYP1A2 | |
| SCHEMBL4183137 | 0.82 | LMNA (0.50) | HTTLMNAKDM4EPOLBTSHR | |
| SCHEMBL1245338 | 0.82 | LMNA (0.50) | HTTLMNAKDM4EPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046350-A1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-02-23 | — | — | US | disclosed |
| US-20110184186-A1 | PROCESS FOR PREPARING LIGANDS OF PPARDELTA AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2011-07-28 | — | — | US | disclosed |
| US-20110184186-A1 | PROCESS FOR PREPARING LIGANDS OF PPARDELTA AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2011-07-28 | — | — | US | disclosed |
| US-7982050-B2 | Process for preparing ligands of PPARdelta and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2011-07-19 | — | — | US | disclosed |
| US-7982050-B2 | Process for preparing ligands of PPARdelta and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2011-07-19 | — | — | US | disclosed |
| US-7816385-B2 | Dimeric dicarboxylic acid derivatives, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC (US) | 2010-10-19 | — | — | US | disclosed |
| US-7816385-B2 | Dimeric dicarboxylic acid derivatives, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC (US) | 2010-10-19 | — | — | US | disclosed |
| US-7816385-B2 | Dimeric dicarboxylic acid derivatives, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC (US) | 2010-10-19 | — | — | US | disclosed |
| EP-1558572-B1 | NOVEL COMPOUNDS AND THEIR USE AS PRAR-MODULATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-06-30 | — | — | EP | disclosed |
| EP-1558571-B1 | NOVEL COMPOUNDS USEFUL IN TREATING PPAR MEDIATED DISEASES | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-06-02 | — | — | EP | disclosed |
| US-20040143006-A1 | Novel compounds, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC | 2004-07-22 | — | — | US | disclosed |
| EP-1438283-A1 | DICARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE | NOVO NORDISK A/S (DK) | 2004-07-21 | — | — | EP | disclosed |
| WO-2004056740-A1 | DICARBOXYLIC ACID DERIVATIVES AS PPAR-AGONISTS | NOVO NORDISK A/S (DK) | 2004-07-08 | — | — | WO | disclosed |
| WO-2004037776-A2 | NOVEL COMPOUNDS AND THEIR USE AS PRAR-MODULATORS | NOVO NORDISK A/S (DK) | 2004-05-06 | — | — | WO | disclosed |
| WO-2004037775-A1 | NOVEL COMPOUNDS USEFUL IN TREATING PPAR MEDIATED DISEASES | NOVO NORDISK A/S (DK) | 2004-05-06 | — | — | WO | disclosed |
| WO-2004022533-A1 | NOVEL VINYL CARBOXYLIC ACID DERIVATIVES AND THEIR THERAPEUTICAL USE | NOVO NORDISK A/S (DK) | 2004-03-18 | — | — | WO | disclosed |
| US-20030225158-A1 | Compounds that modulate PPAR activity and methods for their preparation | WARNER-LAMBERT COMPANY | 2003-12-04 | — | — | US | disclosed |
| WO-2003084916-A2 | COMPOUNDS THAT MODULATE PPAR ACTIVITY AND METHODS FOR THEIR PREPARATION | WARNER-LAMBERT COMPANY LLC (US) | 2003-10-16 | — | — | WO | disclosed |
| US-20030109579-A1 | Novel compounds, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC | 2003-06-12 | — | — | US | disclosed |
| WO-2003033453-A1 | DICARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE | NOVO NORDISK A/S (DK) | 2003-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109579-A1 | Novel compounds, their preparation and use | PPARG, PPARA, PPARD | HTT 3193/4885LMNA 1974/4885KDM4E 3030/4885 |
| US-20110184186-A1 | PROCESS FOR PREPARING LIGANDS OF PPARDELTA AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | PPARG, PPARD, PPARA | HTT 1967/4885LMNA 1497/4885KDM4E 4310/4885 |
| US-20030225158-A1 | Compounds that modulate PPAR activity and methods for their preparation | GPR119, PPARA, PPARG | HTT 614/4885LMNA 1929/4885KDM4E 2934/4885 |
| US-20040143006-A1 | Novel compounds, their preparation and use | PPARG, PPARD, PPARA | HTT 2981/4885LMNA 1433/4885KDM4E 4475/4885 |
| US-20120046350-A1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | PPARG, PPARD, PPARA | HTT 2775/4885LMNA 1393/4885KDM4E 4443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.