Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 7/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18691989 | 0.85 | LMNA (0.41) | MAOBMAOALMNATDP1KDM1A | |
| SCHEMBL146501 | 0.85 | LMNA (0.41) | MAOBMAOALMNATDP1KDM1A | |
| SCHEMBL15518760 | 0.83 | LMNA (0.40) | MAOBMAOALMNAKDM1A | |
| Ethylene SCHEMBL4942079 | 0.81 | LMNA (0.39) | MAOBMAOALMNAKDM1A | |
| SCHEMBL6570377 | 0.80 | CYP1A2 (0.48) | MEN1KMT2AMAOBMAOALMNA | |
| SCHEMBL4943423 | 0.80 | MMP3 (0.48) | MEN1KMT2ALMNATDP1KDM1A | |
| SCHEMBL6572088 | 0.80 | PTGS1 (0.40) | MEN1KMT2AMAOBMAOALMNA | |
| SCHEMBL4941871 | 0.77 | ALDH1A1 (0.37) | MEN1KMT2AHPGDTDP1NPC1 | |
| SCHEMBL4942556 | 0.76 | ALDH1A1 (0.45) | MAOBLMNATSHRPOLBKDM1A | |
| SCHEMBL27593860 | 0.75 | HSD17B10 (0.38) | MAOBMAOALMNATDP1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404446-A2 | CATALYST COMPRISING CHROMIUM AND A LIGAND COMPRISING A SUBSTITUTED CYCLOPENTADIENE AND ITS USE FOR TRIMERISING OLEFINS | Sasol Technology (Proprietary) Limited (ZA) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003004158-A2 | CATALYST COMPRISING CHROMIUM AND A LIGAND COMPRISING A SUBSTITUTED CYCLOPENTADIENE AND ITS USE FOR TRIMERISING OLEFINS | SASOL TECHNOLOGY (PROPRIETARY) LIMITED (ZA) | 2003-01-16 | — | — | WO | disclosed |