Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568870 | 1.00 | GAA (0.45) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL6570110 | 0.90 | TLR9 (0.46) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL6570109 | 0.90 | TLR9 (0.46) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL6570287 | 0.88 | TLR9 (0.51) | GAAMAPTALDH1A1TLR9MEN1 | |
| SCHEMBL6570281 | 0.88 | TLR9 (0.51) | GAAMAPTALDH1A1TLR9MEN1 | |
| SCHEMBL6568880 | 0.82 | TLR9 (0.45) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL6568877 | 0.82 | TLR9 (0.45) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL6570168 | 0.82 | MAPT (0.46) | GAAMAPTALDH1A1TLR9MEN1 | |
| SCHEMBL6567333 | 0.79 | ALDH1A1 (0.54) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL6567337 | 0.79 | ALDH1A1 (0.54) | GAAMGAMSIMGAM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483227-A1 | THE PURIFICATION OF 2-METHOXY-5-TRIFLUOROMETHOXYBENZALDEHYDE | Pfizer Products Inc. (US) | 2004-12-08 | — | — | EP | claimed |
| US-6686507-B2 | IMINATION BY REACTING WITH A NITROANILINE; ISOLATING SOLID; LIQUEFACTION AND CONVERTING BACK | PFIZER INC | 2004-02-03 | — | — | US | claimed |
| US-20030176741-A1 | Purification of 2-methoxy-5-trifluoromethoxybenzaldehyde | PFIZER INC. | 2003-09-18 | — | — | US | claimed |
| WO-2003074462-A1 | THE PURIFICATION OF 2-METHOXY-5-TRIFLUOROMETHOXYBENZALDEHYDE | PFIZER PRODUCTS INC. (US) | 2003-09-12 | — | — | WO | claimed |
| EP-1483227-A1 | THE PURIFICATION OF 2-METHOXY-5-TRIFLUOROMETHOXYBENZALDEHYDE | Pfizer Products Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| US-6686507-B2 | IMINATION BY REACTING WITH A NITROANILINE; ISOLATING SOLID; LIQUEFACTION AND CONVERTING BACK | PFIZER INC | 2004-02-03 | — | — | US | disclosed |
| US-20030176741-A1 | Purification of 2-methoxy-5-trifluoromethoxybenzaldehyde | PFIZER INC. | 2003-09-18 | — | — | US | disclosed |
| WO-2003074462-A1 | THE PURIFICATION OF 2-METHOXY-5-TRIFLUOROMETHOXYBENZALDEHYDE | PFIZER PRODUCTS INC. (US) | 2003-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176741-A1 | Purification of 2-methoxy-5-trifluoromethoxybenzaldehyde | TH, PNMT, INMT | GAA 2413/4885MGAM 166/4885SI 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.