Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943355 | 1.00 | TSHR (0.76) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL9065069 | 0.95 | TSHR (0.81) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| Acrylic Acid Ethyl Ester SCHEMBL690098 | 0.91 | TSHR (0.71) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| Acrylic Acid Ethyl Ester SCHEMBL28293402 | 0.91 | TSHR (0.67) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL4901912 | 0.91 | TSHR (0.74) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL11820168 | 0.90 | TSHR (0.72) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL5512435 | 0.90 | TSHR (0.72) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL7756201 | 0.90 | TSHR (0.72) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL14777949 | 0.90 | TSHR (0.76) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL1931959 | 0.90 | TSHR (0.76) | TSHRCYP3A4TDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401587-A1 | COATINGS APPROPRIATE FOR MEDICAL DEVICES | Biocoat Incorporated (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100559-A1 | COATINGS APPROPRIATE FOR MEDICAL DEVICES | BIOCOAT INCORPORATED (US) | 2002-12-19 | — | — | WO | disclosed |