Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065761 | 0.82 | MAPT (0.35) | MAPTMAPK1NPSR1L3MBTL1NAAA | |
| SCHEMBL8474376 | 0.82 | MAPT (0.35) | MAPTMAPK1NPSR1L3MBTL1NAAA | |
| SCHEMBL6567152 | 0.81 | CA12 (0.31) | — | |
| SCHEMBL729753 | 0.80 | NPSR1 (0.37) | MAPTMAPK1NPSR1L3MBTL1NAAA | |
| SCHEMBL728349 | 0.77 | ALDH1A1 (0.35) | MAPTMAPK1NPSR1L3MBTL1NAAA | |
| SCHEMBL728425 | 0.76 | ALDH1A1 (0.37) | MAPTMAPK1NPSR1L3MBTL1NAAA | |
| SCHEMBL4164878 | 0.75 | CYP1A2 (0.33) | L3MBTL1HSD17B10 | |
| SCHEMBL729761 | 0.71 | ALDH1A1 (0.37) | MAPTMAPK1NPSR1L3MBTL1NAAA | |
| SCHEMBL4452598 | 0.71 | MAPT (0.35) | MAPTMAPK1NPSR1L3MBTL1NAAA | |
| SCHEMBL4452594 | 0.71 | MAPT (0.35) | MAPTMAPK1NPSR1L3MBTL1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831108-B1 | Curable silane-endcapped compositions having improved performance | CROMPTON CORP (US) | 2004-04-07 | — | — | EP | disclosed |
| US-6001946-A | Curable silane-encapped compositions having improved performances | WITCO CORPORATION (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0831108-A1 | Curable silane-endcapped compositions having improved performance | OSi Specialties, Inc. (US) | 1998-03-25 | — | — | EP | disclosed |