SCHEMBL728349

SCHEMBL728349

CCCCOC(=O)CC(NC[Si](OC)(OC)OCC)C(=O)OCCCC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
MAPT P10636 2/20 0.35
LMNA P02545 2/20 0.35
HPGD P15428 2/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NPSR1 Q6W5P4 3/20 0.35
MAPK1 P28482 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NAAA Q02083 1/20 0.34
PPARG P37231 2/20 0.33
NCOA2 Q15596 2/20 0.33
NCOA1 Q15788 2/20 0.33
RXFP1 Q9HBX9 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
FAAH O00519 1/20 0.33
ALPG P10696 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 2/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728425 0.99 ALDH1A1 (0.37) ALDH1A1MAPTLMNAHPGDTSHR
SCHEMBL729761 0.95 ALDH1A1 (0.37) ALDH1A1MAPTLMNAHPGDTSHR
SCHEMBL729753 0.93 NPSR1 (0.37) ALDH1A1MAPTLMNAHPGDTSHR
SCHEMBL728606 0.85 L3MBTL1 (0.39) ALDH1A1MAPTHPGDTSHRHSD17B10
SCHEMBL728669 0.83 L3MBTL1 (0.38) ALDH1A1MAPTTSHRHSD17B10L3MBTL1
SCHEMBL4452598 0.83 MAPT (0.35) ALDH1A1MAPTLMNAHPGDTSHR
SCHEMBL4452594 0.83 MAPT (0.35) ALDH1A1MAPTLMNAHPGDTSHR
SCHEMBL730268 0.82 CA12 (0.30)
SCHEMBL7065761 0.82 MAPT (0.35) ALDH1A1MAPTLMNAHSD17B10NPSR1
SCHEMBL8474376 0.82 MAPT (0.35) ALDH1A1MAPTLMNAHSD17B10NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed