SCHEMBL729753

SCHEMBL729753

CCCCOC(=O)CC(NC[Si](OC)(OC)OC)C(=O)OCCCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 4/20 0.37
MAPT P10636 2/20 0.37
MAPK1 P28482 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NAAA Q02083 1/20 0.37
ALDH1A1 P00352 4/20 0.36
FAAH O00519 1/20 0.35
HPGD P15428 3/20 0.34
PPARG P37231 2/20 0.34
NCOA2 Q15596 2/20 0.34
NCOA1 Q15788 2/20 0.34
LMNA P02545 2/20 0.34
RXFP1 Q9HBX9 1/20 0.34
NCOA3 Q9Y6Q9 1/20 0.34
ATM Q13315 1/20 0.34
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALPG P10696 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728349 0.93 ALDH1A1 (0.35) NPSR1MAPTMAPK1L3MBTL1NAAA
SCHEMBL728425 0.92 ALDH1A1 (0.37) NPSR1MAPTMAPK1L3MBTL1NAAA
SCHEMBL729761 0.87 ALDH1A1 (0.37) NPSR1MAPTMAPK1L3MBTL1NAAA
SCHEMBL7065761 0.85 MAPT (0.35) NPSR1MAPTMAPK1L3MBTL1NAAA
SCHEMBL8474376 0.85 MAPT (0.35) NPSR1MAPTMAPK1L3MBTL1NAAA
SCHEMBL728627 0.82 L3MBTL1 (0.44) MAPTL3MBTL1ALDH1A1HPGDHTT
SCHEMBL6569060 0.80 MAPT (0.32) NPSR1MAPTMAPK1L3MBTL1NAAA
SCHEMBL9702988 0.78 MAPT (0.40) NPSR1MAPTMAPK1L3MBTL1NAAA
SCHEMBL15689224 0.77 NPSR1 (0.44) NPSR1MAPTMAPK1L3MBTL1NAAA
SCHEMBL8581960 0.77 NAAA (0.44) NPSR1MAPTMAPK1L3MBTL1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102361901-B Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MAT INC 2014-06-11 CN claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
CN-102361901-B Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MAT INC 2014-06-11 CN disclosed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed