Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569100 | 0.89 | MEN1 (0.38) | PTGS1PTGS2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6568369 | 0.83 | MEN1 (0.38) | PTGS1PTGS2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6570380 | 0.81 | HTR1A (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6569451 | 0.78 | PARP1 (0.38) | CYP1A2CYP3A4CYP2D6CYP2C19MEN1 | |
| SCHEMBL6569280 | 0.78 | TAAR1 (0.39) | CYP3A4CYP2D6MEN1KMT2ANPSR1 | |
| SCHEMBL6567663 | 0.77 | USP2 (0.36) | PTGS1PTGS2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6569390 | 0.76 | SCN9A (0.33) | CYP2D6KMT2ANPSR1 | |
| SCHEMBL15397097 | 0.75 | PTGS1 (0.38) | PTGS1PTGS2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25760610 | 0.75 | PTGS1 (0.38) | PTGS1PTGS2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25463696 | 0.75 | ALOX15 (0.39) | CYP1A2CYP2D6CYP2C9SMN1; SMN2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405851-A1 | Method for producing seven-membered diether compounds and intermediates thereof | Takasago International Corporation (JP) | 2004-04-07 | — | — | EP | disclosed |