Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568369 | 0.94 | MEN1 (0.38) | MEN1KMT2APTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL6569071 | 0.89 | PTGS1 (0.36) | MEN1KMT2APTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL6567663 | 0.88 | USP2 (0.36) | MEN1KMT2APTGS1PTGS2ALDH1A1 | |
| SCHEMBL6569150 | 0.82 | USP2 (0.36) | MEN1KMT2APTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL28614086 | 0.81 | KDM4E (0.40) | SMN1; SMN2ALDH1A1NPC1RAB9ASLC6A2 | |
| SCHEMBL6567367 | 0.81 | KDM4E (0.40) | SMN1; SMN2ALDH1A1NPC1RAB9ASLC6A2 | |
| SCHEMBL6567593 | 0.79 | PARP1 (0.39) | MEN1KMT2AMAPTNPSR1CYP1A2 | |
| SCHEMBL6568390 | 0.79 | TAAR1 (0.40) | MEN1KMT2AMAPTNPSR1CYP3A4 | |
| SCHEMBL6569246 | 0.77 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1MAPTNPSR1 | |
| SCHEMBL6569112 | 0.77 | SCN9A (0.34) | KMT2ANPSR1CYP2D6TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405851-A1 | Method for producing seven-membered diether compounds and intermediates thereof | Takasago International Corporation (JP) | 2004-04-07 | — | — | EP | disclosed |