Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 10/20 | 0.36 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | TYK2 | P29597 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31003285 | 0.84 | CYP11B1 (0.36) | UGT2B7HTR2AHTR2C | |
| SCHEMBL31204862 | 0.80 | ACSS2 (0.34) | SMPD3 | |
| SCHEMBL20731021 | 0.74 | SMPD3 (0.45) | SMPD3HTR2AHTR2C | |
| SCHEMBL33995 | 0.74 | SMPD3 (0.38) | SMPD3HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL33849 | 0.73 | SMPD3 (0.40) | SMPD3 | |
| SCHEMBL1230140 | 0.72 | ADRB2 (0.31) | — | |
| SCHEMBL26596835 | 0.71 | FYN (0.32) | SMPD3 | |
| SCHEMBL23385229 | 0.70 | SMPD3 (0.38) | SMPD3 | |
| SCHEMBL28626251 | 0.70 | EPHB3 (0.43) | SMPD3 | |
| SCHEMBL20731024 | 0.70 | EPHB3 (0.45) | SMPD3HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372586-A1 | OXIDATION DYEING COMPOSITION CONTAINING 3-AMINO PYRAZOLO- 1,5-A]-PYRIDINE AND ONE AMINOPHENOL COUPLING AGENT | L'OREAL (FR) | 2004-01-02 | — | — | EP | claimed |
| WO-2002076419-A1 | OXIDATION DYEING COMPOSITION CONTAINING 3-AMINO PYRAZOLO-[1,5-A]-PYRIDINE AND ONE AMINOPHENOL COUPLING AGENT | L'OREAL (FR) | 2002-10-03 | — | — | WO | claimed |
| US-11504318-B2 | Symmetric azomethine direct dyes, process for their preparation, cosmetic composition comprising at least one such dye and use thereof | L'OREAL (FR) | 2022-11-22 | — | — | US | disclosed |
| CN-111094232-A | P-phenylenediamine color bases F having an aliphatic chain and trialkylammonium groups and use thereof for oxidation dyeing of keratin fibers | 莱雅公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-111032008-A | Method for dyeing keratin materials using at least one blue, violet or green dye and at least one disulfide, thiol or protected thiol fluorescent dye | 莱雅公司 | 2020-04-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11504318-B2 | Symmetric azomethine direct dyes, process for their preparation, cosmetic composition comprising at least one such dye and use thereof | KRT18, IK, H1-5 | SMPD3 3585/4885UGT2B7 3419/4885JAK2 4806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.