SCHEMBL6569150

SCHEMBL6569150

CCC(C)c1ccc2c(c1)OCC(O)(CCl)O2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
AOC3 Q16853 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6567663 0.95 USP2 (0.36) USP2ALDH1A1GAAPKMHPGD
SCHEMBL6568369 0.88 MEN1 (0.38) ALDH1A1PKMPTGS1PTGS2AOC3
SCHEMBL6569100 0.82 MEN1 (0.38) ALDH1A1PKMPTGS1PTGS2AOC3
SCHEMBL6570547 0.77 KDM4E (0.40) ALDH1A1GAAKDM4ESMN1; SMN2
SCHEMBL28609664 0.77 KDM4E (0.40) ALDH1A1GAAKDM4ESMN1; SMN2
SCHEMBL6569099 0.77 TAAR1 (0.36) HPGDMEN1KMT2AKDM4ECYP3A4
SCHEMBL6567576 0.76 TAAR1 (0.35) HPGDALOX15CYP2D6SMN1; SMN2NPSR1
SCHEMBL6569219 0.76 TAAR1 (0.38) GAAHPGDALOX15CYP3A4CYP2D6
SCHEMBL6568390 0.75 TAAR1 (0.40) GAAALOX15MEN1KMT2ACYP3A4
SCHEMBL6570579 0.75 CALM1 (0.38) HPGDHDAC2HDAC8NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1405851-A1 Method for producing seven-membered diether compounds and intermediates thereof Takasago International Corporation (JP) 2004-04-07 EP disclosed