Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28609664 | 1.00 | KDM4E (0.40) | KDM4EHTR1ASLC6A2HTR2CHTR2B | |
| SCHEMBL6567367 | 0.94 | KDM4E (0.40) | KDM4EHTR1ASLC6A2HTR2CHTR2B | |
| SCHEMBL28614086 | 0.94 | KDM4E (0.40) | KDM4EHTR1ASLC6A2HTR2CHTR2B | |
| SCHEMBL6569136 | 0.88 | HTR1A (0.38) | KDM4EHTR1ASLC6A2HTR2CHTR2B | |
| SCHEMBL6570380 | 0.81 | HTR1A (0.38) | KDM4EHTR1ASLC6A2HTR2CHTR2B | |
| SCHEMBL6568369 | 0.81 | MEN1 (0.38) | SLC6A2NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6569099 | 0.81 | TAAR1 (0.36) | KDM4E | |
| SCHEMBL6570579 | 0.79 | CALM1 (0.38) | NPC1RAB9AHTT | |
| SCHEMBL6569068 | 0.78 | ALOX15 (0.39) | HTTSMN1; SMN2 | |
| SCHEMBL6569150 | 0.77 | USP2 (0.36) | KDM4EGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405851-A1 | Method for producing seven-membered diether compounds and intermediates thereof | Takasago International Corporation (JP) | 2004-04-07 | — | — | EP | disclosed |