SCHEMBL6569152

SCHEMBL6569152

CCCN(CCC)c1ccccc1C(=O)c1ccccc1N(CCC)CCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.57
TP53 P04637 4/20 0.57
ALDH1A1 P00352 4/20 0.57
GAA P10253 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
MAPT P10636 1/20 0.57
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
CNR2 P34972 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.39
HCAR3 P49019 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
BCHE P06276 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CRHR1 P34998 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP3A4 P08684 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27666331 0.90 TP53 (0.47) TSHRTP53ALDH1A1GAASMN1; SMN2
SCHEMBL6569225 0.89 TSHR (0.53) TSHRTP53ALDH1A1GAASMN1; SMN2
SCHEMBL6567717 0.87 ALDH1A1 (0.52) TSHRTP53ALDH1A1GAASMN1; SMN2
SCHEMBL4086031 0.87 TP53 (0.52) TSHRTP53ALDH1A1GAASMN1; SMN2
SCHEMBL6567797 0.86 ALDH1A1 (0.50) TSHRTP53ALDH1A1GAASMN1; SMN2
SCHEMBL6566239 0.86 ALDH1A1 (0.50) TSHRTP53ALDH1A1GAASMN1; SMN2
SCHEMBL6568005 0.86 ALDH1A1 (0.50) TSHRTP53ALDH1A1GAASMN1; SMN2
SCHEMBL6567779 0.86 ALDH1A1 (0.50) TSHRTP53ALDH1A1GAASMN1; SMN2
SCHEMBL6567311 0.86 ALDH1A1 (0.50) TSHRTP53ALDH1A1GAASMN1; SMN2
SCHEMBL6569140 0.86 ALDH1A1 (0.50) TSHRTP53ALDH1A1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0939102-B1 Rubber compounds containing aromatic ketone polysulfides GOODYEAR TIRE & RUBBER (US) 2004-04-07 EP disclosed
US-6303821-B1 IMPROVE THE POLYMER-FILLER INTERACTION OF ELASTOMERS OR RUBBERS. THE GOODYEAR TIRE & RUBBER COMPANY 2001-10-16 US disclosed
US-6277926-B1 PROCESSING RUBBER BY MIXING WITH A BIS-(4-AMINOPHENYL)-CARBONYL-(1,4-PHENYLENE)-POLYSUFIDE TO INCREASE THE MOONEY VISCOSITY I.E. STIFFNESS; IMPROVED POLYMER/FILLER INTERACTION; RECEPTIVITY THE GOODYEAR TIRE & RUBBER COMPANY 2001-08-21 US disclosed
US-6075096-A BIS(ALKYLAMINO)BENZOPHENONES BRIDGED TOGETHER BY A POLYSULFIDE GROUP (SX, X=2-8) WHICH ACTS TO IMPROVE THE POLYMER-FILLER INTERACTION OF ELASTOMERS OR RUBBERS; FORMED COMPOSITE PRODUCTS SUCH AS TIRES, SHOE HEELS THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-06-13 US disclosed
EP-0939102-A2 Rubber compounds containing aromatic ketone polysulfides THE GOODYEAR TIRE & RUBBER COMPANY (US) 1999-09-01 EP disclosed