Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 10/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 10/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 10/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 10/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 10/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 10/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.36 |
| ▸ | CHRNG | P07510 | 9/20 | 0.36 |
| ▸ | CHRND | Q07001 | 9/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569199 | 0.86 | CHRNA1 (0.34) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL6569281 | 0.80 | CHRNA1 (0.30) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL6567176 | 0.80 | CHRNA1 (0.30) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL6567946 | 0.78 | KDM1A (0.44) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL509943 | 0.71 | CYP4F2 (0.38) | CHRNB4CHRNA3CYP4F2CYP4A11 | |
| SCHEMBL15778022 | 0.69 | PANK3 (0.41) | SLC6A2SLC6A3SLC6A4CYP4F2CYP4A11 | |
| SCHEMBL6457272 | 0.67 | OPRL1 (0.31) | — | |
| SCHEMBL6451589 | 0.67 | CHRNA1 (0.31) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL6451585 | 0.67 | CHRNA1 (0.31) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL3907530 | 0.65 | NUDT1 (0.46) | SLC6A2SLC6A3SLC6A4CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919536-B1 | Fluorine-substituted 4-alkenylbenzoic acid and derivatives thereof, and nematic liquid crystal composition containing cyanophenyl benzoate derivatives and liquid crystal display system using the same | DAINIPPON INK & CHEMICALS (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6693223-B1 | STRONG POLAR COMPOUND HAVING LARGE DIELECTRIC ANISOTROPY; EXERTS EXCELLENT THRESHOLD VOLTAGE REDUCING EFFECT; EXCELLENT MISCIBILITY WITH CONVENTIONAL LIQUID CRYSTAL MATERIALS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2004-02-17 | — | — | US | disclosed |
| US-20020053659-A1 | Fluorine-substituted-4-alkenylbenzoic acid and derivatives thereof, and nematic liquid crystal composition containing cyanophenyl benzoate derivatives and liquid crystal display system using the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-09 | — | — | US | disclosed |
| US-6287646-B1 | MIXTURES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-0919536-A1 | Fluorine-substituted 4-alkenylbenzoic acid and derivatives thereof, and nematic liquid crystal composition containing cyanophenyl benzoate derivatives and liquid crystal display system using the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-06-02 | — | — | EP | disclosed |