Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13186431 | 0.81 | MAOB (0.41) | FYNCLK4DYRK1BKMT2ANPC1 | |
| SCHEMBL12987176 | 0.79 | TNKS (0.44) | KMT2ANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL2128898 | 0.79 | KIF11 (0.45) | NPC1RAB9AALDH1A1MAPTNFKB1 | |
| SCHEMBL28647816 | 0.79 | MAOB (0.45) | KMT2ANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL1542864 | 0.77 | RXRA (0.44) | KMT2ANPC1RAB9AALDH1A1NFKB1 | |
| SCHEMBL149989 | 0.77 | MAPT (0.57) | CLK4NPC1RAB9AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL29878602 | 0.75 | MAPT (0.55) | CLK4NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL11465256 | 0.75 | MAPT (0.60) | CLK4NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL3342855 | 0.75 | LMNA (0.48) | NPC1RAB9AALDH1A1MAPTNFKB1 | |
| SCHEMBL2100162 | 0.74 | NOTUM (0.55) | NPC1RAB9AALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138329-B1 | Composition containing 5-Methyl-1-phenyl-2-(1 H)-pyridone for reparation and prevention of fibrotic lesions | YAMAUCHI SHITOTOMO (JP) | 2004-06-02 | — | — | EP | claimed |
| EP-0383591-B1 | Use of 5-methyl-1-phenyl-2-(1H)-pyridone in the prevention of fibrotic lesions | YAMAUCHI SHITOTOMO (JP) | 2001-11-21 | — | — | EP | claimed |