Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.52 |
| ▸ | PI4KA | P42356 | 2/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.52 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.52 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.52 |
| ▸ | GAPDH | P04406 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | STAT6 | P42226 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL939590 | 0.92 | ADORA3 (0.54) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL10441571 | 0.91 | ADORA3 (0.50) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL937577 | 0.89 | ADORA3 (0.47) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL1723481 | 0.88 | ADORA3 (0.47) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL28715703 | 0.88 | ADORA3 (0.50) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL4650244 | 0.87 | ADORA3 (0.47) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL11516446 | 0.87 | PI4KA (0.47) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL940812 | 0.86 | ADORA3 (0.45) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL703597 | 0.86 | ADORA3 (0.46) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL1900941 | 0.85 | AHCY (0.46) | ADORA3ADORA2API4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727959-B1 | DIAGNOSTIC USES OF HYDRAZINOADENOSINES | ADERIS PHARMACEUTICALS INC (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-0727959-A4 | DIAGNOSTIC USES OF HYDRAZINOADENOSINES | DISCOVERY THERAPEUTICS INC (US) | 2000-11-08 | — | — | EP | disclosed |
| EP-0567094-B1 | Hydrazoadenosines | DISCOVERY THERAPEUTICS INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0727959-A1 | DIAGNOSTIC USES OF HYDRAZINOADENOSINES | Discovery Therapeutics, Inc. (US) | 1996-08-28 | — | — | EP | disclosed |
| US-5477857-A | Measuring myocardial function in mammals | DISCOVERY THERAPEUTICS, INC. (US) | 1995-12-26 | — | — | US | disclosed |
| WO-1995007049-A1 | DIAGNOSTIC USES OF HYDRAZINOADENOSINES | DISCOVERY THERAPEUTICS, INC. (US) | 1995-03-16 | — | — | WO | disclosed |
| EP-0567094-A2 | Hydrazoadenosines | Discovery Therapeutics, Inc. (US) | 1993-10-27 | — | — | EP | disclosed |