Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.46 |
| ▸ | PI4KA | P42356 | 2/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.46 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30666098 | 0.90 | ADORA3 (0.43) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL6569314 | 0.86 | ADORA3 (0.52) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL939590 | 0.85 | ADORA3 (0.54) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL10441571 | 0.84 | ADORA3 (0.50) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL1723481 | 0.84 | ADORA3 (0.47) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL29982099 | 0.83 | ADORA3 (0.44) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL30198845 | 0.82 | ADORA3 (0.50) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL28715703 | 0.82 | ADORA3 (0.50) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL1434028 | 0.81 | ADORA3 (0.49) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL4650244 | 0.81 | ADORA3 (0.47) | ADORA3ADORA2API4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007090553-A2 | COMPOUNDS USEFUL AS AGONISTS OF A2A ADENOSINE RECEPTORS, COSMETIC COMPOSITIONS WITH A2A AGONISTS AND A METHOD FOR USING THE SAME | UNILEVER PLC (GB) | 2007-08-16 | — | — | WO | claimed |
| US-20070183995-A1 | Compounds useful as agonists of A2A adenosine receptors, cosmetic compositions with A2A agonists and a method for using the same | CONOPCO, INC., D/B/A UNILEVER | 2007-08-09 | — | — | US | claimed |
| WO-1994023723-A1 | ADENOSINE RECEPTOR AGONISTS FOR THE PROMOTION OF WOUND HEALING | NEW YORK UNIVERSITY (US) | 1994-10-27 | — | — | WO | claimed |
| CN-101378725-B | Is suitable for use as A2AAdenosine receptor agonist compounds containing A2ACosmetic compositions of agonists and methods of use thereof | UNILEVER NV | 2014-03-12 | — | — | CN | disclosed |
| US-8124729-B2 | Splice variants of human G-protein coupled receptor HGPRBMY29 (HGPRMBY29SV2) | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-02-28 | — | — | US | disclosed |
| US-20120010385-A1 | SPLICE VARIANTS OF HUMAN G-PROTEIN COUPLED RECEPTOR HGPRBMY29 (HGPRMBY29SV2) | BRISTOL-MYERS SQUIBB COMPANY | 2012-01-12 | — | — | US | disclosed |
| US-7713699-B2 | Methods of diagnosing colon adenocarcinoma using mRNA encoding the human g-protein coupled receptor, HGPRBMY23 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-05-11 | — | — | US | disclosed |
| US-7635758-B2 | Antibodies directed to G-protein coupled receptor HGPRBMY29sv1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-12-22 | — | — | US | disclosed |
| CN-101378725-A | Is suitable for use as A2AAdenosine receptor agonist compounds containing A2ACosmetic compositions of agonists and methods of use thereof | UNILEVER PLC (NL) | 2009-03-04 | — | — | CN | disclosed |
| US-20080213918-A1 | Polynucleotides encoding two novel human G-protein coupled receptors, HGPRBMY28 and HGPRBMY29, and splice variants thereof | BRISTOL-MYERS SQUIBB COMPANY | 2008-09-04 | — | — | US | disclosed |
| US-7417121-B2 | Human G-protein coupled receptor, HGPRBMY39 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-08-26 | — | — | US | disclosed |
| US-20030064381-A1 | Polynucleotide encoding a novel human G-protein coupled receptor, HGPRBMY26, expressed highly in testis and gastrointestinal tissues | BRISTOL-MYERS SQUIBB COMPANY | 2003-04-03 | — | — | US | disclosed |
| US-20030060409-A1 | Polynucleotide encoding a novel human G-protein coupled receptor, HGPRBMY25, expressed highly in immune-related tissues | BRISTOL-MYERS SQUIBB COMPANY | 2003-03-27 | — | — | US | disclosed |
| US-20030054374-A1 | Polynucleotide encoding a novel human G-protein coupled receptor, HGPRBMY27 | BRISTOL-MYERS SQUIBB COMPANY | 2003-03-20 | — | — | US | disclosed |
| WO-2003023007-A2 | POLYNUCLEOTIDE ENCODING A NOVEL HUMAN G-PROTEIN COUPLED RECEPTOR, HGPRBMY39 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-03-20 | — | — | WO | disclosed |
| WO-2002096946-A1 | POLYNUCLEOTIDE ENCODING A NOVEL HUMAN G-PROTEIN COUPLED RECEPTOR, HGPRBMY30 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-12-05 | — | — | WO | disclosed |
| WO-2002086123-A2 | A HUMAN G-PROTEIN COUPLED RECEPTOR, HGPRBMY11, EXPRESSED HIGHLY IN HEART AND VARIANTS THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-10-31 | — | — | WO | disclosed |
| WO-2002083856-A2 | POLYNUCLEOTIDES ENCODING TWO NOVEL HUMAN G-PROTEIN COUPLED RECEPTORS, HGPRBMY28 AND HGPRBMY29, AND SPLICE VARIANTS THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-10-24 | — | — | WO | disclosed |
| WO-2002072755-A2 | POLYNUCLEOTIDE ENCODING A NOVEL HUMAN G-PROTEIN COUPLED RECEPTOR, HGPRBMY27 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-09-19 | — | — | WO | disclosed |
| WO-2002046414-A2 | HUMAN G-PROTEIN COUPLED RECEPTOR EXPRESSED HIGHLY IN KIDNEY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070183995-A1 | Compounds useful as agonists of A2A adenosine receptors, cosmetic compositions with A2A agonists and a method for using the same | ADORA2A, ADORA3, ADORA1 | ADORA3 2/4885ADORA2A 1/4885PI4KA 2506/4885 |
| US-20030054374-A1 | Polynucleotide encoding a novel human G-protein coupled receptor, HGPRBMY27 | GIPR, GPR27, MRGPRX2 | ADORA3 324/4885ADORA2A 948/4885PI4KA 2562/4885 |
| US-20120010385-A1 | SPLICE VARIANTS OF HUMAN G-PROTEIN COUPLED RECEPTOR HGPRBMY29 (HGPRMBY29SV2) | GPR39, GIPR, GPR4 | ADORA3 297/4885ADORA2A 584/4885PI4KA 2216/4885 |
| US-20030064381-A1 | Polynucleotide encoding a novel human G-protein coupled receptor, HGPRBMY26, expressed highly in testis and gastrointestinal tissues | GIPR, GPR180, GPR3 | ADORA3 381/4885ADORA2A 1065/4885PI4KA 3214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.