SCHEMBL65695

SCHEMBL65695

C=C(C)C(=O)Oc1ccc(C(C)(C)c2cc(OCC)c(OC(=O)C(=C)C)c(OCC)c2OCC)c(OCCC)c1OCCC

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
TSHR P16473 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
MAPT P10636 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
KDM4E B2RXH2 1/20 0.30
CREBBP Q92793 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29771328 1.00 MEN1 (0.36) MEN1KMT2ATSHRCYP1A2CYP2C9
SCHEMBL29114642 1.00 MEN1 (0.36) MEN1KMT2ATSHRCYP1A2CYP2C9
SCHEMBL6386501 0.95 MAPT (0.33) MEN1KMT2ACYP1A2CYP2C19MAPT
SCHEMBL66400 0.95 TSHR (0.35) MEN1KMT2ATSHRCYP1A2CYP2C9
SCHEMBL29771136 0.95 TSHR (0.35) MEN1KMT2ATSHRCYP1A2CYP2C9
SCHEMBL32674607 0.93 MEN1 (0.32) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL23149337 0.93 MEN1 (0.33) MEN1KMT2A
SCHEMBL32674610 0.92 MEN1 (0.33) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL3685897 0.92 MEN1 (0.33) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL392038 0.88 MEN1 (0.34) MEN1KMT2ATSHRMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 401 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240108555-A1 UNREACTIVE TRANSFER SPLINTS VOCO GMBH (DE) 2024-04-04 US claimed
EP-4338702-A1 NON-REACTIVE TRANSFER RAILS VOCO GmbH (DE) 2024-03-20 EP claimed
US-9925124-B2 Dental composition suitable for grinding with automatic grinding apparatus KABUSHIKI KAISHA SHOFU (JP) 2018-03-27 US claimed
US-4898899-A Adhesive composition TOAGOSEI CHEMICAL INDUSTRY CO. (JP) 1990-02-06 US claimed
EP-4091578-B1 METHOD FOR PRODUCING PLATE DENTURE TOKUYAMA DENTAL CORP (JP) 2024-10-09 EP disclosed
WO-2024150826-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-07-18 WO disclosed
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same KURARAY CO., LTD. (JP) 2024-07-09 US disclosed
US-20240199494-A1 ZIRCONIA MOLDED BODY, ZIRCONIA PRE-SINTERED BODY, AND ZIRCONIA SINTERED BODY, AND METHODS OF PRODUCTION THEREOF Kuraray Noritake Dental lnc. (JP) 2024-06-20 US disclosed
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT SHOFU INC. (JP) 2024-05-30 US disclosed
US-20240173212-A1 HIGH TRANSPARENCY AND LONG-RELEASE DENTAL RESIN COMPOSITION CONTAINING CORE-SHELL POROUS STRUCTURED NANOPARTICLES AND METHOD FOR PREPARING THE SAME JNP Nature Co., Ltd. (KR) 2024-05-30 US disclosed
US-20240164993-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME KURARAY NORITAKE DENTAL INC. (JP) 2024-05-23 US disclosed
EP-3848418-B1 DENTAL CURABLE COMPOSITION AND METHOD FOR PRODUCING DENTAL CURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2024-05-22 EP disclosed
US-5260476-A Dental restoration TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1993-11-09 US disclosed
US-5171763-A A dental composite of a monomer containing poly(3,4-carboxylic benzoic acid and acrylic ester moities, an ion leachable filler and an initiator; high adhesion and strength; discoloration inhibition TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
US-4898899-A Adhesive composition TOAGOSEI CHEMICAL INDUSTRY CO. (JP) 1990-02-06 US disclosed
US-4394494-A DIURETHANE TETRAACRYLATES AS POLYMERIZABLE MONOMERS LION CORPORATION (JP) 1983-07-19 US disclosed
US-4388421-A PRIMERS LION CORPORATION (JP) 1983-06-14 US disclosed
US-4383052-A 1-Methacryloxyethane-1,1-diphosphonic acid and its salts and dental adhesive composition containing same LION CORPORATION (JP) 1983-05-10 US disclosed
US-4055542-A PEROXIDE THREE BOND CO., LTD. (JA) 1977-10-25 US disclosed
US-4044044-A Anaerobic adhesive composition containing 0.05 to 20 parts per weight of phosphate esters of hydroxyacrylates per 100 parts per weight of polymerizable acrylic ester monomer SAITO TSUTOMU 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same ARL1, ASH2L, VCL MEN1 2530/4885KMT2A 1501/4885TSHR 4710/4885
US-20240108555-A1 UNREACTIVE TRANSFER SPLINTS MATR3, SUGT1, DIMT1 MEN1 2935/4885KMT2A 124/4885TSHR 4744/4885
US-20240164993-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME MSL1, ITGA1, ASH2L MEN1 1398/4885KMT2A 1162/4885TSHR 4172/4885
US-20240173211-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT GRIK1, GRIN2B, GRIK2 MEN1 3341/4885KMT2A 455/4885TSHR 2655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.