SCHEMBL66400

SCHEMBL66400

C=C(C)C(=O)Oc1ccc(C(C)(C)c2cc(OCC)c(OC(=O)C(=C)C)c(OCC)c2OCC)c(OCC)c1OCC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CREBBP Q92793 1/20 0.33
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
GAA P10253 2/20 0.32
HSD17B10 Q99714 2/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 2/20 0.32
HPGD P15428 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
RORC P51449 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPC1 O15118 1/20 0.32
USP2 O75604 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29771136 1.00 TSHR (0.35) TSHRCYP1A2CYP2C9CYP2C19MEN1
SCHEMBL29114642 0.95 MEN1 (0.36) TSHRCYP1A2CYP2C9CYP2C19MEN1
SCHEMBL29771328 0.95 MEN1 (0.36) TSHRCYP1A2CYP2C9CYP2C19MEN1
SCHEMBL65695 0.95 MEN1 (0.36) TSHRCYP1A2CYP2C9CYP2C19MEN1
SCHEMBL305556 0.93 TSHR (0.40) TSHRCYP1A2CYP2C9CYP2C19MEN1
SCHEMBL32674605 0.93 EGFR (0.33) TSHRCYP1A2CYP2C9CYP2C19
SCHEMBL32674608 0.92 TSHR (0.32) TSHRCYP1A2CYP2C9CYP2C19MEN1
SCHEMBL29415623 0.90 CYP1A2 (0.35) TSHRCYP1A2CYP2C9CYP2C19MEN1
SCHEMBL64707 0.90 CYP1A2 (0.35) TSHRCYP1A2CYP2C9CYP2C19MEN1
SCHEMBL6386501 0.89 MAPT (0.33) CYP1A2CYP2C19MEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240108555-A1 UNREACTIVE TRANSFER SPLINTS VOCO GMBH (DE) 2024-04-04 US claimed
EP-4306099-A1 METHOD FOR PRODUCING DENTAL MILL BLANKS VOCO GmbH (DE) 2024-01-17 EP claimed
US-20240008963-A1 PROCESS FOR THE PRODUCTION OF DENTAL MILLING BLANKS VOCO GMBH (DE) 2024-01-11 US claimed
EP-2623087-B1 Dental composite materials containing tricyclic plasticisers VOCO GMBH (DE) 2019-07-17 EP claimed
EP-2623086-B1 Curable mixture comprising plasticisers with a polyalicyclic structure element for use in the production of dental materials. VOCO GMBH (DE) 2019-07-10 EP claimed
US-9925124-B2 Dental composition suitable for grinding with automatic grinding apparatus KABUSHIKI KAISHA SHOFU (JP) 2018-03-27 US claimed
US-9314408-B2 Dental composite materials comprising tricyclic plasticizers VOCO GMBH (DE) 2016-04-19 US claimed
US-20130203884-A1 DENTAL COMPOSITE MATERIALS COMPRISING TRICYCLIC PLASTICIZERS VOCO GMBH (DE) 2013-08-08 US claimed
EP-2623086-A2 Curable mixture comprising plasticisers with a polyalicyclic structure element for use in the production of dental materials. VOCO GmbH (DE) 2013-08-07 EP claimed
EP-2623087-A2 Dental composite materials containing tricyclic plasticisers VOCO GmbH (DE) 2013-08-07 EP claimed
US-4898899-A Adhesive composition TOAGOSEI CHEMICAL INDUSTRY CO. (JP) 1990-02-06 US claimed
EP-4091578-B1 METHOD FOR PRODUCING PLATE DENTURE TOKUYAMA DENTAL CORP (JP) 2024-10-09 EP disclosed
WO-2024150826-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-07-18 WO disclosed
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same KURARAY CO., LTD. (JP) 2024-07-09 US disclosed
US-20240199494-A1 ZIRCONIA MOLDED BODY, ZIRCONIA PRE-SINTERED BODY, AND ZIRCONIA SINTERED BODY, AND METHODS OF PRODUCTION THEREOF Kuraray Noritake Dental lnc. (JP) 2024-06-20 US disclosed
US-4898899-A Adhesive composition TOAGOSEI CHEMICAL INDUSTRY CO. (JP) 1990-02-06 US disclosed
US-4394494-A DIURETHANE TETRAACRYLATES AS POLYMERIZABLE MONOMERS LION CORPORATION (JP) 1983-07-19 US disclosed
US-4388421-A PRIMERS LION CORPORATION (JP) 1983-06-14 US disclosed
US-4383052-A 1-Methacryloxyethane-1,1-diphosphonic acid and its salts and dental adhesive composition containing same LION CORPORATION (JP) 1983-05-10 US disclosed
US-4044044-A Anaerobic adhesive composition containing 0.05 to 20 parts per weight of phosphate esters of hydroxyacrylates per 100 parts per weight of polymerizable acrylic ester monomer SAITO TSUTOMU 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same ARL1, ASH2L, VCL TSHR 4710/4885CYP1A2 3079/4885CYP2C9 3128/4885
US-20240108555-A1 UNREACTIVE TRANSFER SPLINTS MATR3, SUGT1, DIMT1 TSHR 4744/4885CYP1A2 2851/4885CYP2C9 3479/4885
US-20130203884-A1 DENTAL COMPOSITE MATERIALS COMPRISING TRICYCLIC PLASTICIZERS CAD, PBRM1, PCBP1 TSHR 3986/4885CYP1A2 2309/4885CYP2C9 1866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.