Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569565 | 1.00 | ALOX15 (0.46) | ALOX15EPHX2TRPV1NFE2L2CYP19A1 | |
| SCHEMBL6569570 | 0.88 | ALOX15 (0.44) | ALOX15EPHX2TRPV1NFE2L2 | |
| SCHEMBL6569569 | 0.88 | ALOX15 (0.44) | ALOX15EPHX2TRPV1NFE2L2 | |
| SCHEMBL7899286 | 0.82 | CNR2 (0.39) | — | |
| SCHEMBL7899283 | 0.82 | CNR2 (0.39) | — | |
| SCHEMBL6569562 | 0.79 | ALOX15 (0.56) | ALOX15EPHX2NFE2L2 | |
| SCHEMBL6569564 | 0.79 | ALOX15 (0.56) | ALOX15EPHX2NFE2L2 | |
| SCHEMBL6568168 | 0.79 | TDP1 (0.45) | TRPV1 | |
| SCHEMBL6568165 | 0.79 | TDP1 (0.45) | TRPV1 | |
| SCHEMBL7907066 | 0.78 | MAPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0887336-B1 | Precursor compounds | GIVAUDAN SA (CH) | 2004-01-07 | — | — | EP | claimed |
| US-6207857-B1 | FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2001-03-27 | — | — | US | claimed |
| EP-0887336-B1 | Precursor compounds | GIVAUDAN SA (CH) | 2004-01-07 | — | — | EP | disclosed |
| US-6207857-B1 | FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2001-03-27 | — | — | US | disclosed |
| EP-0887336-A1 | Precursor Compounds | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1998-12-30 | — | — | EP | disclosed |