Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907069 | 1.00 | MAPT (0.41) | MAPTTP53GAARAB9AALDH1A1 | |
| SCHEMBL7899283 | 0.94 | CNR2 (0.39) | RAB9AALDH1A1KDM4ECNR2SMN1; SMN2 | |
| SCHEMBL7899286 | 0.94 | CNR2 (0.39) | RAB9AALDH1A1KDM4ECNR2SMN1; SMN2 | |
| SCHEMBL6566596 | 0.83 | CNR2 (0.41) | RAB9AALDH1A1KDM4ECNR2SMN1; SMN2 | |
| SCHEMBL6566598 | 0.83 | CNR2 (0.41) | RAB9AALDH1A1KDM4ECNR2SMN1; SMN2 | |
| SCHEMBL7905574 | 0.82 | CNR2 (0.49) | GAARAB9AALDH1A1LMNACNR2 | |
| SCHEMBL6568187 | 0.81 | LMNA (0.50) | MAPTRAB9AALDH1A1LMNAKDM4E | |
| SCHEMBL6568186 | 0.81 | LMNA (0.50) | MAPTRAB9AALDH1A1LMNAKDM4E | |
| SCHEMBL6568168 | 0.81 | TDP1 (0.45) | RAB9AALDH1A1LMNACNR2SMN1; SMN2 | |
| SCHEMBL6568165 | 0.81 | TDP1 (0.45) | RAB9AALDH1A1LMNACNR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207857-B1 | FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2001-03-27 | — | — | US | claimed |
| US-6207857-B1 | FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2001-03-27 | — | — | US | disclosed |
| EP-0887336-A1 | Precursor Compounds | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1998-12-30 | — | — | EP | disclosed |