SCHEMBL6569571

SCHEMBL6569571

C=CC(N)NC(=N)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
CES1 P23141 2/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
TGM2 P21980 1/20 0.41
LMNA P02545 3/20 0.41
GAA P10253 1/20 0.41
ALDH1A1 P00352 2/20 0.40
MAPK1 P28482 1/20 0.40
CCNA2 P20248 1/20 0.39
CDK2 P24941 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.39
CES2 O00748 1/20 0.38
SRD5A2 P31213 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SLC1A3 P43003 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6569555 0.83 PRSS1 (0.54) TSHRCES1LMNAALDH1A1CCNA2
SCHEMBL17469781 0.76 MAPK1 (0.50) TSHRCES1CA1CA2TDP1
SCHEMBL8348890 0.74 TSHR (0.55) TSHRCES1CA1CA2TDP1
SCHEMBL9754754 0.73 CA1 (0.50) CA1CA2TGM2LMNAGAA
SCHEMBL17459822 0.73 MAPT (0.59) TSHRCES1CA1CA2TDP1
Hydrochloric Acid SCHEMBL16600504 0.73 TSHR (0.53) TSHRCES1CA1CA2TDP1
SCHEMBL70669 0.72 CES1 (0.55) TSHRCES1CA1CA2TDP1
SCHEMBL28517308 0.71 MAPK1 (0.55) TSHRCES1CA1CA2TDP1
SCHEMBL9300709 0.71 ALDH1A1 (0.47) TSHRCA1CA2TDP1TGM2
SCHEMBL5778212 0.70 MAPK1 (0.50) TSHRCES1CA1CA2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1408026-A1 Alpha-amino-N-allylamidino nitrobenzene compound and synthesis EASTMAN KODAK COMPANY (US) 2004-04-14 EP claimed
US-6555711-B1 Reacting an N-allylimino nitrobenzene compound with a diamino-dinucleophile to form an alpha-amino-N- allylamidino-nitrobenzene compound; chemical intermediate for a pyrazolo(1,5-b)(1,2,4)triazole color photographic coupler EASTMAN KODAK COMPANY 2003-04-29 US claimed