SCHEMBL6569555

SCHEMBL6569555

C=CC(N)NC(=N)c1cccc([N+](=O)[O-])c1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.54
PRSS2 P07478 1/20 0.54
PRSS3 P35030 1/20 0.54
TSHR P16473 2/20 0.49
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
TP53 P04637 1/20 0.47
KMO O15229 1/20 0.46
ALDH1A1 P00352 2/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
LMNA P02545 1/20 0.43
CCNA2 P20248 1/20 0.43
CDK2 P24941 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6569571 0.83 TSHR (0.44) TSHRCES2CES1ALDH1A1LMNA
SCHEMBL3551362 0.77 PRSS1 (0.66) PRSS1PRSS2PRSS3TSHRCES2
Hydrochloric Acid SCHEMBL4399781 0.76 PRSS1 (0.69) PRSS1PRSS2PRSS3TSHRCES2
SCHEMBL2227754 0.75 PRSS1 (0.63) PRSS1PRSS2PRSS3TSHRCES2
SCHEMBL9300488 0.74 TSHR (0.52) TSHRALDH1A1KMT2AMEN1LMNA
SCHEMBL14599583 0.74 PRSS1 (0.61) PRSS1PRSS2PRSS3TSHRCES2
SCHEMBL2762350 0.72 PRSS1 (0.96) PRSS1PRSS2PRSS3TSHRCES2
SCHEMBL24933536 0.71 ALDH1A1 (0.64) PRSS1PRSS2PRSS3TSHRCES2
Hydrochloric Acid SCHEMBL1262882 0.70 PRSS1 (1.00) PRSS1PRSS2PRSS3TSHRCES2
SCHEMBL5093354 0.69 CES2 (0.66) PRSS1PRSS2PRSS3TSHRCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1408026-A1 Alpha-amino-N-allylamidino nitrobenzene compound and synthesis EASTMAN KODAK COMPANY (US) 2004-04-14 EP claimed
US-6555711-B1 Reacting an N-allylimino nitrobenzene compound with a diamino-dinucleophile to form an alpha-amino-N- allylamidino-nitrobenzene compound; chemical intermediate for a pyrazolo(1,5-b)(1,2,4)triazole color photographic coupler EASTMAN KODAK COMPANY 2003-04-29 US claimed