Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269067 | 0.79 | CA1 (0.54) | CA1CA12MMP2MMP9MMP8 | |
| SCHEMBL9300709 | 0.77 | ALDH1A1 (0.47) | CA1CA12TGM2ALDH1A1HSD17B10 | |
| SCHEMBL6269658 | 0.76 | TGM2 (0.54) | CA1CA12MMP2MMP9MMP8 | |
| SCHEMBL10600425 | 0.75 | TGM2 (0.50) | CA1CA12MMP2MMP9MMP8 | |
| SCHEMBL6701324 | 0.74 | ALDH1A1 (0.53) | CA1CA12MMP2MMP9MMP8 | |
| SCHEMBL9097720 | 0.74 | CA1 (0.54) | CA1CA12CA2MEN1KMT2A | |
| SCHEMBL6569571 | 0.73 | TSHR (0.44) | CA1TGM2ALDH1A1CA2MAPT | |
| SCHEMBL5498504 | 0.73 | ALDH1A3 (0.37) | ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11858122 | 0.72 | TGM2 (0.58) | CA1CA12MMP2MMP9MMP8 | |
| SCHEMBL3141855 | 0.72 | KCNH3 (0.63) | CA1CA12MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013881-A1 | PARAPHENYLENEDIAMINE DERIVATIVES AND THEIR USE IN OXIDATIVE DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-09-19 | — | — | WO | claimed |