SCHEMBL6570080

SCHEMBL6570080

C1=C(c2ccccc2)C=C(c2ccccc2)C1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.39
HTR2C P28335 1/20 0.38
ALDH1A1 P00352 3/20 0.36
LMNA P02545 1/20 0.36
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CFTR P13569 1/20 0.30
GOPC Q9HD26 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1028408 1.00 SIGMAR1 (0.39) SIGMAR1HTR2CALDH1A1LMNANPC1
SCHEMBL9430369 0.77 ALDH1A1 (0.33) SIGMAR1HTR2CALDH1A1LMNANPC1
SCHEMBL13321308 0.77 KDM4E (0.43) ALDH1A1LMNANPC1RAB9APKM
SCHEMBL28295103 0.74 ALDH1A1 (0.35) ALDH1A1
SCHEMBL1824459 0.74 ALDH1A1 (0.35) ALDH1A1LMNAHPGD
SCHEMBL6250597 0.74 SIGMAR1 (0.38) SIGMAR1HTR2CALDH1A1LMNANPC1
SCHEMBL7635776 0.74 ALDH1A1 (0.35) ALDH1A1LMNAHPGD
SCHEMBL27549604 0.74 CYP1A2 (0.37) ALDH1A1LMNAHPGD
SCHEMBL893700 0.73
Hydrochloric Acid SCHEMBL27521224 0.73 ALDH1A1 (0.33) HTR2CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1404446-A2 CATALYST COMPRISING CHROMIUM AND A LIGAND COMPRISING A SUBSTITUTED CYCLOPENTADIENE AND ITS USE FOR TRIMERISING OLEFINS Sasol Technology (Proprietary) Limited (ZA) 2004-04-07 EP claimed
WO-2003004158-A2 CATALYST COMPRISING CHROMIUM AND A LIGAND COMPRISING A SUBSTITUTED CYCLOPENTADIENE AND ITS USE FOR TRIMERISING OLEFINS SASOL TECHNOLOGY (PROPRIETARY) LIMITED (ZA) 2003-01-16 WO claimed
JP-63160879-A None JP disclosed
EP-0540108-B1 Catalyst composition SHELL INT RESEARCH (NL) 1996-01-03 EP disclosed
US-5279999-A Catalyst composition SHELL OIL COMPANY (US) 1994-01-18 US disclosed
EP-0540108-A1 Catalyst composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-05-05 EP disclosed
JP-S63160879-A THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD 1988-07-04 JP disclosed