SCHEMBL1028408

SCHEMBL1028408

C1=C(c2ccccc2)C=C(c2ccccc2)C1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.39
HTR2C P28335 1/20 0.38
ALDH1A1 P00352 3/20 0.36
LMNA P02545 1/20 0.36
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CFTR P13569 1/20 0.30
GOPC Q9HD26 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6570080 1.00 SIGMAR1 (0.39) SIGMAR1HTR2CALDH1A1LMNANPC1
SCHEMBL9430369 0.77 ALDH1A1 (0.33) SIGMAR1HTR2CALDH1A1LMNANPC1
SCHEMBL13321308 0.77 KDM4E (0.43) ALDH1A1LMNANPC1RAB9APKM
SCHEMBL28295103 0.74 ALDH1A1 (0.35) ALDH1A1
SCHEMBL1824459 0.74 ALDH1A1 (0.35) ALDH1A1LMNAHPGD
SCHEMBL6250597 0.74 SIGMAR1 (0.38) SIGMAR1HTR2CALDH1A1LMNANPC1
SCHEMBL7635776 0.74 ALDH1A1 (0.35) ALDH1A1LMNAHPGD
SCHEMBL27549604 0.74 CYP1A2 (0.37) ALDH1A1LMNAHPGD
SCHEMBL893700 0.73
Hydrochloric Acid SCHEMBL27521224 0.73 ALDH1A1 (0.33) HTR2CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993478-B2 OLEFIN POLYMERIZATION PROCESS BOREALIS TECH OY (FI) 2011-01-19 EP claimed
US-6921799-B1 Olefin polymerization process BOREALIS A/S (DK) 2005-07-26 US claimed
EP-0993478-B1 OLEFIN POLYMERIZATION PROCESS BOREALIS TECH OY (FI) 2004-04-07 EP claimed
EP-0993478-A1 OLEFIN POLYMERIZATION PROCESS BOREALIS A/S (DK) 2000-04-19 EP claimed
WO-1998058001-A1 OLEFIN POLYMERIZATION PROCESS COCKBAIN, JULIAN (GB) 1998-12-23 WO claimed
CN-111448226-B Polymerization process 埃克森美孚化学专利公司 2023-08-25 CN disclosed
CN-111587256-B Catalyst system and polymerization process using the same 埃克森美孚化学专利公司 2023-05-19 CN disclosed
CN-111278872-B Polyethylene compositions and articles made therefrom 埃克森美孚化学专利公司 2022-10-28 CN disclosed
EP-2459600-B1 ORGANOMETALLIC TRANSITION METAL COMPOUND, CATALYST SYSTEM AND PREPARATION OF POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2013-11-20 EP disclosed
US-8471050-B2 Organometallic transition metal compound, catalyst system and preparation of polyolefins BASELL POLYOLEFINE GMBH (DE) 2013-06-25 US disclosed
EP-1261660-B2 PROCESS FOR ADDITION OF ADDITIVES TO POLYMER PARTICLES BOREALIS TECH OY (FI) 2012-11-21 EP disclosed
US-20120142874-A1 Organometallic Transition Metal Compound, Catalyst System and Preparation of Polyolefins BASELL POLYOLEFINE GMBH (DE) 2012-06-07 US disclosed
WO-2000050466-A1 OLEFIN POLYMERISATION PROCESS BOREALIS TECHNOLOGY OY (FI) 2000-08-31 WO disclosed
WO-2000034341-A2 CATALYST AND PROCESS FOR OLEFIN POLYMERIZATION BOREALIS A/S (DK) 2000-06-15 WO disclosed
WO-2000022011-A2 SUPPORTED POLYMERIZATION CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2000-04-20 WO disclosed
EP-0993478-A1 OLEFIN POLYMERIZATION PROCESS BOREALIS A/S (DK) 2000-04-19 EP disclosed
WO-2000011065-A1 POLYMER FOR ROTOMOULDING BOREALIS TECHNOLOGY OY (FI) 2000-03-02 WO disclosed
WO-2000001739-A1 CATALYST FOR THE POLYMERISATION OF OLEFINS BOREALIS TECHNOLOGY OY (FI) 2000-01-13 WO disclosed
WO-1999065949-A2 OLEFIN POLYMERIZATION PROCESS BOREALIS TECHNOLOGY OY (FI) 1999-12-23 WO disclosed
WO-1998058001-A1 OLEFIN POLYMERIZATION PROCESS COCKBAIN, JULIAN (GB) 1998-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142874-A1 Organometallic Transition Metal Compound, Catalyst System and Preparation of Polyolefins PRMT9, INTS9, ACAD9 SIGMAR1 867/4885HTR2C 4574/4885ALDH1A1 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.