Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491564 | 0.87 | SIGMAR1 (0.76) | SIGMAR1HRH3ACHEALDH1A1KDM4E | |
| SCHEMBL6052607 | 0.82 | SIGMAR1 (0.65) | SIGMAR1HRH3ACHEALDH1A1KDM4E | |
| SCHEMBL14114294 | 0.79 | LMNA (0.47) | HRH3LMNA | |
| SCHEMBL17285905 | 0.79 | SIGMAR1 (0.97) | SIGMAR1ACHEALDH1A1USP2CCR3 | |
| SCHEMBL14114297 | 0.79 | FFAR1 (0.45) | LMNA | |
| SCHEMBL17285907 | 0.78 | SIGMAR1 (0.74) | SIGMAR1HRH3ACHEALDH1A1KDM4E | |
| SCHEMBL4444793 | 0.78 | FFAR1 (0.44) | LMNA | |
| SCHEMBL4434541 | 0.78 | LMNA (0.46) | HRH3LMNA | |
| SCHEMBL13504052 | 0.78 | SIGMAR1 (0.88) | SIGMAR1HRH3ACHEALDH1A1USP2 | |
| SCHEMBL12741679 | 0.76 | HRH3 (0.61) | SIGMAR1HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428820-A1 | Non-imidazole alkylamines as histamine H-3-receptor ligands and their therapeutic applications | BIOPROJET (FR) | 2004-06-16 | — | — | EP | disclosed |