Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 5/20 | 0.52 |
| ▸ | MITF | O75030 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417999 | 0.86 | POLB (0.76) | ALDH1A1CYP2C9KMT2AMEN1CYP3A4 | |
| SCHEMBL6030738 | 0.86 | POLB (0.76) | ALDH1A1CYP2C9KMT2AMEN1CYP3A4 | |
| SCHEMBL14706934 | 0.84 | ERCC1 (0.58) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL7930525 | 0.83 | ALDH1A1 (0.69) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4006392 | 0.83 | HPGD (0.69) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL10369646 | 0.81 | KMT2A (0.68) | ALDH1A1KMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL18530331 | 0.81 | ALDH1A1 (0.67) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7076641 | 0.81 | GSTO1 (0.57) | ALDH1A1CYP3A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31042937 | 0.80 | POLB (0.53) | ALDH1A1KMT2ASMN1; SMN2HPGDMAPT | |
| SCHEMBL917175 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CYP2C9CYP2C19KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064267-B1 | NOVEL CATIONIC COUPLING AGENTS, THEIR USE FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | OREAL (FR) | 2004-09-29 | — | — | EP | disclosed |
| US-6461389-B1 | HAIR DYE | L'OREAL S.A. (FR) | 2002-10-08 | — | — | US | disclosed |
| EP-1064267-A1 | NOVEL CATIONIC COUPLING AGENTS, THEIR USE FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999048874-A1 | NOVEL CATIONIC COUPLING AGENTS, THEIR USE FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 1999-09-30 | — | — | WO | disclosed |
| US-5009880-A | Mixture of an anionic and cationic polymer for shampoos, skin lotions, nail strengtheners and hair dyeing; improved fixing and anchoring; smoothness; gloss | L'OREAL (FR) | 1991-04-23 | — | — | US | disclosed |
| US-4719099-A | ANIONIC AND CATIONIC | L'OREAL (FR) | 1988-01-12 | — | — | US | disclosed |
| US-4445521-A | ANIONIC AND CATIONIC POLYMER COMBINATION | L'OREAL (FR) | 1984-05-01 | — | — | US | disclosed |
| US-4240450-A | HAIR CONDITIONER OF ANIONIC POLYMERS AND CATIONIC POLYMERS | L'OREAL (FR) | 1980-12-23 | — | — | US | disclosed |