Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | GSTO1 | P78417 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060481 | 0.85 | KMT2A (0.58) | POLBSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL9821015 | 0.83 | ALDH1A1 (0.48) | SMN1; SMN2GSTO1ALDH1A1HTTLMNA | |
| SCHEMBL14706934 | 0.81 | ERCC1 (0.58) | POLBSMN1; SMN2GSTO1ALDH1A1HTT | |
| SCHEMBL31254026 | 0.81 | SMN1; SMN2 (0.72) | POLBSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL1258654 | 0.81 | SMN1; SMN2 (0.72) | POLBSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL917175 | 0.81 | ALDH1A1 (0.55) | POLBSMN1; SMN2GSTO1ALDH1A1HTT | |
| SCHEMBL6570247 | 0.80 | ALDH1A1 (0.69) | POLBSMN1; SMN2GSTO1ALDH1A1HTT | |
| SCHEMBL7076641 | 0.78 | GSTO1 (0.57) | SMN1; SMN2GSTO1ALDH1A1HTTLMNA | |
| SCHEMBL9768522 | 0.78 | ALDH1A1 (0.62) | POLBSMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL8307201 | 0.77 | POLB (0.74) | POLBSMN1; SMN2ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658647-A1 | TRICYCLIC AZEPINONE DERIVATIVES AS SYSTEM XC INHIBITORS | UCB Biopharma SRL (BE) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024160722-A1 | TRICYCLIC AZEPINONE DERIVATIVES AS SYSTEM XC INHIBITORS | UCB Biopharma SRL (BE) | 2024-08-08 | — | — | WO | disclosed |