Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CRAT | P43155 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL4748810 | 0.98 | BBOX1 (0.38) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL1263610 | 0.88 | TSHR (0.38) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL8156135 | 0.83 | NPSR1 (0.39) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL1617824 | 0.81 | TSHR (0.42) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL6674801 | 0.79 | BBOX1 (0.33) | BBOX1KMT2A | |
| Glycinebetaine SCHEMBL4618092 | 0.78 | TSHR (0.43) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL8651387 | 0.78 | TSHR (0.48) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL2803780 | 0.78 | TSHR (0.53) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL8678519 | 0.78 | TSHR (0.53) | BBOX1TSHRALDH1A1LMNAAPEX1 | |
| Glycinebetaine SCHEMBL4900209 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040013738-A1 | Encapsulation of liquid template particles | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFREN E.V. (DE) | 2004-01-22 | — | — | US | disclosed |