Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1154368 | 0.82 | — | — | |
| SCHEMBL4861380 | 0.80 | — | — | |
| Glycinebetaine SCHEMBL6570314 | 0.79 | BBOX1 (0.39) | BBOX1KMT2A | |
| Glycinebetaine SCHEMBL4748810 | 0.78 | BBOX1 (0.38) | BBOX1 | |
| Sulfur Dioxide SCHEMBL28461511 | 0.77 | TSHR (0.33) | KMT2A | |
| Glycinebetaine SCHEMBL8156135 | 0.75 | NPSR1 (0.39) | BBOX1MEN1KMT2A | |
| Glycinebetaine SCHEMBL5682310 | 0.75 | CHRM5 (0.38) | BBOX1MEN1CYP1A2HRH1KMT2A | |
| Glycinebetaine SCHEMBL15228159 | 0.74 | CHRM5 (0.35) | BBOX1MEN1CYP1A2HRH1KMT2A | |
| Glycinebetaine SCHEMBL1617824 | 0.72 | TSHR (0.42) | BBOX1MEN1CYP1A2HRH1KMT2A | |
| Glycinebetaine SCHEMBL1263610 | 0.72 | TSHR (0.38) | BBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004148173-A | HARMFUL SUBSTANCE CLEANING CATALYST AND ITS MANUFACTURING PROCESS | TOYOTA CENTRAL RES & DEV LAB INC | 2004-05-27 | — | — | JP | disclosed |