Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498757 | 0.92 | EGFR (0.58) | MAPTMEN1KMT2ARAB9AEGFR | |
| SCHEMBL4950655 | 0.86 | MAPT (0.68) | MAPTMEN1KMT2ANOX1GAA | |
| SCHEMBL6573923 | 0.85 | MAPT (0.54) | MAPTMEN1KMT2ANOX1GAA | |
| SCHEMBL10498369 | 0.81 | SMN1; SMN2 (0.68) | MAPTMEN1KMT2ANOX1GAA | |
| SCHEMBL9013674 | 0.80 | ALDH1A1 (0.55) | MAPTMEN1KMT2ANOX1GAA | |
| SCHEMBL11133186 | 0.79 | MAPT (0.48) | MAPTMEN1KMT2ANOX1GAA | |
| SCHEMBL11476653 | 0.79 | MEN1 (0.67) | MAPTMEN1KMT2ANOX1GAA | |
| SCHEMBL28147367 | 0.79 | HDAC6 (0.62) | MAPTMEN1KMT2AGAARAB9A | |
| Methanesulfonamide SCHEMBL10826157 | 0.78 | MEN1 (0.49) | MAPTMEN1KMT2ANOX1GAA | |
| SCHEMBL7471413 | 0.77 | EGFR (0.58) | MAPTMEN1KMT2ANOX1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928289-B1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | OREAL (FR) | 2004-09-29 | — | — | EP | disclosed |
| US-6638321-B1 | Oxidation color dyes for hair from aniline compounds | L'OREAL (FR) | 2003-10-28 | — | — | US | disclosed |
| EP-0928289-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 1999-07-14 | — | — | EP | disclosed |
| WO-1999003836-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 1999-01-28 | — | — | WO | disclosed |