SCHEMBL6573923

SCHEMBL6573923

CCN(CCO)c1ccc(NC(C)=O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.54
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
NOX1 Q9Y5S8 3/20 0.54
GAA P10253 2/20 0.54
POLB P06746 2/20 0.54
MCL1 Q07820 2/20 0.54
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53
ALDH1A1 P00352 4/20 0.49
THRB P10828 2/20 0.49
KDM4E B2RXH2 1/20 0.49
RECQL P46063 1/20 0.49
CNR2 P34972 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
HPGD P15428 2/20 0.49
NFKB1 P19838 1/20 0.49
KCNH2 Q12809 1/20 0.49
HSD17B10 Q99714 1/20 0.49
TSHR P16473 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methanesulfonamide SCHEMBL10826157 0.91 MEN1 (0.49) MAPTMEN1KMT2ANOX1GAA
SCHEMBL4950655 0.88 MAPT (0.68) MAPTMEN1KMT2ANOX1GAA
SCHEMBL6570518 0.85 MAPT (0.53) MAPTMEN1KMT2ANOX1GAA
SCHEMBL9357969 0.83 RAB9A (0.51) MAPTMEN1KMT2ANOX1GAA
SCHEMBL10498369 0.83 SMN1; SMN2 (0.68) MAPTMEN1KMT2ANOX1GAA
SCHEMBL8038944 0.82 ALDH1A1 (0.50) MAPTMEN1KMT2ANOX1GAA
SCHEMBL9013674 0.81 ALDH1A1 (0.55) MAPTMEN1KMT2ANOX1GAA
SCHEMBL9615809 0.81 MAPT (0.46) MAPTMEN1KMT2ANOX1GAA
SCHEMBL7039465 0.81 MAPT (0.46) MAPTMEN1KMT2ANOX1GAA
SCHEMBL11133186 0.80 MAPT (0.48) MAPTMEN1KMT2ANOX1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0928289-B1 NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS OREAL (FR) 2004-09-29 EP disclosed
US-6638321-B1 Oxidation color dyes for hair from aniline compounds L'OREAL (FR) 2003-10-28 US disclosed
EP-0928289-A1 NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS L'OREAL (FR) 1999-07-14 EP disclosed
WO-1999003836-A1 NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS L'OREAL (FR) 1999-01-28 WO disclosed
EP-0429234-B1 Radiation sensitive devices AGFA GEVAERT NV (BE) 1998-10-28 EP disclosed
EP-0344985-B1 Radiation sensitive devices DU PONT (US) 1994-08-17 EP disclosed
US-5162193-A With discontinuous covering layer formed by solution or dispersion in liquid hydrocarbon DU PONT-HOWSON LIMITED (GB) 1992-11-10 US disclosed
US-5006442-A Method of forming a discontinuous covering layer on radiation sensitive devices VICKERS PLC (GB) 1991-04-09 US disclosed
EP-0344985-A2 Radiation sensitive devices E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-12-06 EP disclosed
EP-0030862-B2 RADIATION SENSITIVE COMPOUNDS, METHODS OF PRODUCING THEM AND RADIATION SENSITIVE PLATES BASED ON SUCH MATERIALS Vickers Limited (GB) 1987-02-04 EP disclosed
US-4595648-A Radiation-sensitive plates formed using diazonium salts VICKERS LIMITED (GB) 1986-06-17 US disclosed
EP-0030862-B1 RADIATION SENSITIVE COMPOUNDS, METHODS OF PRODUCING THEM AND RADIATION SENSITIVE PLATES BASED ON SUCH MATERIALS Vickers Limited (GB) 1984-10-10 EP disclosed
EP-0030862-A2 Radiation sensitive compounds, methods of producing them and radiation sensitive plates based on such materials Vickers Limited (GB) 1981-06-24 EP disclosed