Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11884522 | 0.87 | ALDH1A1 (0.43) | ALDH1A1HSD17B10SMN1; SMN2NPSR1TP53 | |
| SCHEMBL11073915 | 0.85 | ALDH1A1 (0.49) | ALDH1A1HSD17B10SMN1; SMN2NPSR1TP53 | |
| SCHEMBL4950655 | 0.82 | MAPT (0.68) | ALDH1A1HSD17B10SMN1; SMN2TP53HPGD | |
| SCHEMBL6573923 | 0.81 | MAPT (0.54) | ALDH1A1HSD17B10SMN1; SMN2TP53HPGD | |
| SCHEMBL11494625 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HSD17B10SMN1; SMN2NPSR1TP53 | |
| SCHEMBL22476606 | 0.80 | HDAC1 (0.42) | ALDH1A1HSD17B10SMN1; SMN2NPSR1TP53 | |
| SCHEMBL6570518 | 0.80 | MAPT (0.53) | ALDH1A1HSD17B10SMN1; SMN2TP53HPGD | |
| SCHEMBL11696313 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HSD17B10SMN1; SMN2NPSR1HPGD | |
| SCHEMBL7763575 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HSD17B10SMN1; SMN2NPSR1TP53 | |
| SCHEMBL10498369 | 0.78 | SMN1; SMN2 (0.68) | ALDH1A1HSD17B10SMN1; SMN2NPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569751-A | DIAZOTIZATION; COUPLING | HOECHST MITSUBISHI KASEI CO. (JP) | 1996-10-29 | — | — | US | disclosed |