Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | USP7 | Q93009 | 2/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.40 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.40 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.40 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.40 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.40 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.40 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.40 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571409 | 0.88 | ALDH1A1 (0.48) | ALDH1A1USP7FYNBRD4CHEK2 | |
| SCHEMBL6574565 | 0.81 | MAPT (0.40) | ALDH1A1USP7BRD4MAP4K4MAPT | |
| SCHEMBL6571581 | 0.79 | ALDH1A1 (0.45) | ALDH1A1USP7FYNBRD4CHEK2 | |
| SCHEMBL6570856 | 0.79 | ALDH1A1 (0.38) | ALDH1A1FYNMAP4K4RAB9APOLB | |
| SCHEMBL6573165 | 0.78 | KMO (0.42) | MAP4K4 | |
| SCHEMBL6572182 | 0.77 | PIK3CG (0.41) | ALDH1A1MAP4K4CYP1A2 | |
| Hydrochloric Acid SCHEMBL6572997 | 0.77 | PTGDR2 (0.43) | ALDH1A1CYP11B1CYP11B2RAB9APOLB | |
| SCHEMBL6570709 | 0.76 | ALDH1A1 (0.44) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL6572491 | 0.76 | MAPT (0.37) | ALDH1A1RAB9APOLBNPC1SMN1; SMN2 | |
| SCHEMBL6572172 | 0.76 | STK4 (0.45) | ALDH1A1USP7RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |
| EP-1051143-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999059527-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |